Background and aims The rate of functional cure (HBsAg loss) remains unsatisfactory following pegylated interferon (PEG-IFN) treatment in chronic hepatitis B. To optimize PEG-IFN administration, this study aimed to evaluate virological markers to predict functional cure and/or hepatitis B e antigen (HBeAg) loss. Methods Relevant studies assessing virologic markers for predicting functional cure and HBeAg … Read more
Hong Kong health authorities have warned parents not to “blindly follow” overseas changes to childhood immunisation schedules, including the flu and hepatitis B birth dose, after the US scaled back its routine vaccine recommendations for infants. The Health Department’s Centre for Health Protection issued the warning on Wednesday in response to a controversial overhaul by … Read more
Third asset to advance into clinical trials, validating broad potential of Launch-iT platform All subjects treated with first dose of AVX70371 Launch-iT, as part of multiple dosing schedule Potential first-in-class treatment that could form part of functional cure for over 250 million patients suffering from chronic hepatitis B virus (HBV) infection Leuven, Belgium, June 5, … Read more
In this nationwide, population-based cohort of COVID-19 patients, we found an increased risk of severe COVID-19 (hospitalization, ICU treatment or death) in individuals with chronic HBV infection, even after adjusting for potential confounders. In addition to an increased risk in individuals who were male, elderly, non-vaccinated, and with low- socioeconomic status (SES), the multivariable models … Read more
Since 2026, a new preventive vaccinations calendar will come into force in Ukraine, which has finally been approved by the Ministry of… The post What’s new and why is it important? appeared first on Archyworldys. Source link
Photo: Stepan Popov/Adobe Stock With chronic hepatitis potentially being more common in cats than believed, according to a feline virologist at the City University of Hong Kong, a group of researchers and specialists are coming together to study the first hepatitis B-related virus found in carnivores. Specifically, their research will center on how the virus … Read more
Background and goal: Health care workers are at higher risk of hepatitis B infection due to occupational exposure to blood and body fluids. They are considered protected if they have a hepatitis B surface antigen antibody (anti-HBs) titer of ≥10 mIU/mL after completing a full vaccination series. This study compared the effectiveness of Heplisav-B, a … Read more
With over 600 known human viruses and new ones emerging, experts highlight how climate change, globalization, and zoonotic spillover are accelerating viral threats—are we ready for the next pandemic? Invited Review: Human viruses: An ever-increasing list. Image Credit: Lightspring / Shutterstock In a recent review published in the journal Virology, researchers examined the increasing diversity of human … Read more
In 2024, the WHO updated its guidelines for the prevention, diagnosis, treatment, and care of individuals infected with chronic hepatitis B [5]. The updated guidelines simplify clinical algorithms for the diagnosis, treatment, and monitoring of hepatitis B, expand treatment eligibility criteria, and provide alternative treatment options. The updated guidelines recommend four treatment eligibility options that … Read more
The American Gastroenterology Association (AGA) Institute issued new clinical practice guidelines, providing evidence-based recommendations for managing hepatitis B reactivation (HBVr) in at-risk individuals, emphasizing antiviral prophylaxis for those at high or moderate risk.1 Image credit: Rasi – stock.adobe.com Although antiviral prophylaxis is effective in mitigating the risk, some cases can be managed through clinical monitoring … Read more