helicobacter pylori

Global study reveals disparities in early-onset gastric cancer

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Gastric cancer remains the fifth leading cause of cancer-related deaths worldwide. Although its overall incidence has declined, early-onset cases—diagnosed before age 50—display unique biological and clinical patterns. These include diffuse histologic features, signet ring cell predominance, and poor prognosis. Environmental and lifestyle exposures, such as Helicobacter pylori infection, smoking, and high-salt diets, are known contributors. … Read more

Study finds fewer H. pylori infections among Parkinson’s patients

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Could a common stomach bug help shield the brain from Parkinson’s? New research links H. pylori infection to reduced disease risk, opening fresh avenues in neurodegenerative science. Study: Helicobacter pylori infection might be a protective factor against Parkinson’s disease. Image Credit: Liya Graphics / Shutterstock Around half the world has Helicobacter pylori infections, which are typically linked to … Read more

Fecal microbiota transplantation emerges as a promising approach to H. pylori eradication

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Helicobacter pylori (H. pylori) is a widespread bacterial infection associated with gastritis, peptic ulcers, and gastric cancer. While conventional antibiotic-based treatments have been the gold standard for eradication, their efficacy has been steadily declining due to the alarming rise in antibiotic resistance. This has spurred interest in alternative therapies, one of which is fecal microbiota transplantation … Read more

ACG Issues First Guidance on Gastric Premalignant Conditions

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The American College of Gastroenterology (ACG) has issued its first clinical practice guideline on the diagnosis and management of gastric premalignant conditions (GPMCs) including atrophic gastritis, gastric intestinal metaplasia, dysplasia, and certain gastric epithelial polyps, all of which have an increased risk of progressing to gastric cancer. The guideline was published online on March 12 … Read more

Revolutionizing Understanding: New Study Rethinks Functional Dyspepsia and Gastroparesis

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Archyde Beyond teh Divide: Rethinking Functional Dyspepsia and Gastroparesis in 2025 Table of Contents 1. Beyond teh Divide: Rethinking Functional Dyspepsia and Gastroparesis in 2025 2. The Blurring Lines of Gut Disorders 3. Symptom Overlap: Where Does One Disorder End and Another Begin? 4. Unraveling the Underlying Mechanisms 5. The Gut Microbiome: A Key Player? … Read more

New study challenges traditional view of functional dyspepsia and gastroparesis

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Functional dyspepsia (FD) and gastroparesis (GP) are gastrointestinal disorders often managed as separate conditions. FD is classified as a disorder of gut-brain interaction (DGBI), characterized by symptoms such as early satiety, postprandial fullness, and epigastric pain without structural abnormalities. In contrast, GP is a neuromuscular disorder diagnosed based on delayed gastric emptying (GE), typically presenting … Read more

Efficacy analysis of folic acid in chronic atrophic gastritis with Helicobacter pylori infection: a systematic review and meta-analysis | BMC Gastroenterology

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Literature search and study selection process After conducting an electronic search, 1634 records were identified, 916 of which were kept after removing duplicates. After assessing the titles and abstracts, a further 891 records were excluded, leaving 25 articles to be retrieved for full-text evaluation. In the end, 16 RCTs [27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42] fulfilled the inclusion criteria. Figure 1 … Read more

Triglyceride-glucose index and mortality risks in Helicobacter pylori-infected patients: a national cohort study | BMC Infectious Diseases

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Lv Ypin, Cheng P, Zhang J, yu, Mao F, yuan, Teng Y sheng, Liu Y et al. gang,. Helicobacter pylori–induced matrix metallopeptidase-10 promotes gastric bacterial colonization and gastritis. Sci Adv. 2019;5(4):eaau6547. Tsai CC, Kuo TY, Hong ZW, Yeh YC, Shih KS, Du SY, et al. Helicobacter pylori neutrophil-activating protein induces release of histamine and interleukin-6 … Read more

Biomarker for Upper GI Disorders?

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TOPLINE: Dysbiosis of the oral microbiome is associated with various upper gastrointestinal (UGI) disorders and precancerous lesions, with specific microbial signatures varying by disease and oral site, research shows. METHODOLOGY: Emerging evidence suggests that the oral microbiota may contribute to the development of gastrointestinal malignancies, leading to efforts to identify biomarkers for early detection and … Read more