Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) belong to a spectrum of neurodegenerative diseases with overlapping symptoms, characterized by muscle wasting, paralysis, dementia, and other serious impairments. There are currently no effective treatments. Many patients have a common hallmark: A protein called TDP-43 clumps together in the neurons of the brain to form tiny … Read more
People living with neurological diseases such as Parkinson’s disease, dementia and epilepsy face not only physical decline, but also profound questions about identity, purpose, and meaning. Yet physicians best positioned to address those concerns do not have the adequate training and tools to do so, a new paper states. The paper, published in the journal … Read more
Research in a mouse model of Huntington’s disease has shown that the adult brain can generate new neurons that integrate into key motor circuits. Building on previous work, the new findings, by a team at the Center for Translational Neuromedicine, University of Rochester Medical Center (URMC), demonstrated that stimulating natural brain processes may help repair … Read more