Sizheng Steven Zhao, MBChB, PhD Credit: LinkedIn JAK inhibitor (JAKi) therapy was not associated with an increased risk of cardiovascular disease, venous thromboembolism (VTE), or some cancers in people with psoriatic arthritis (PsA) and spondyloarthritis (SpA) compared to TNF inhibitors (TNFi) or IL-17 inhibitors (IL-17i).1 “Compared to TNFi, tofacitinib was shown to increase risk of … Read more
New research is providing clinicians with an overview of the association between cardiovascular health and the risk of developing metabolic dysfunctional-associated steatotic liver disease (MASLD).1 Leveraging National Health and Nutrition Examination Survey (NHANES) 2017-March 2020 data and using the American Heart Association (AHA)’s Life’s Essential 8 (LE8) score as a benchmark of cardiovascular health, investigators … Read more
Orrin M. Troum, MD, Credit: University of Southern California Pegloticase (Krystexxa; Amgen) was not found to put patients with gout at a higher risk of thromboembolic (TE) and cardiovascular (CV) events, according to a new post-hoc analysis of multiple trials assessing the therapy.1 “In these trials, the proportion of patients experiencing gout flares increased during … Read more
Unveiling the Unique Pathologies of IgA Nephropathy and Nephrotic Syndrome New research is shedding light on notable differences in the clinicopathological characteristics and long-term prognosis of patients with… The post New Research on IgA Nephropathy and Nephrotic Syndrome: Differences in Clinical Features and Long-Term Prognosis appeared first on NewsyList. Source link
New research is shedding light on notable differences in the clinicopathological characteristics and long-term prognosis of patients with IgA nephropathy (IgAN) and nephrotic syndrome (NS) across different pathological phenotypes.1 Study findings suggest differences in the clinical features and renal prognosis of patients with IgAN-NS and minimal change disease (MCD), membranous nephropathy (MN), membranoproliferative glomerulonephritis (IgAN-MPGN), … Read more
Abebaw Yohannes, MSc, PhDCredit: American Lung Association Prevalence of depression: Chronic obstructive pulmonary disease (COPD) is a major cause of disability, morbidity, and premature mortality.1,2 Approximately, two-thirds of COPD patients live with 2 or more comorbidities.4,5 Of these, over 40% suffer from co-morbid depression that warrants medical intervention; however, many remain undiagnosed and thus untreated.6 … Read more
Donghee Kim, MD, PhD Credit: Stanford Medicine New research is providing insight into the prevalence of lean steatotic liver disease (SLD) in the US, addressing potential changes in previous estimates following a 2023 change in liver disease nomenclature.1 Leveraging National Health and Nutrition Examination Survey (NHANES) data from 2017-2023, investigators determined the age-adjusted prevalence of … Read more
Cara L. McDermott, PharmD, PhD Credit: Cancer and Aging Research Group New research has found a large proportion of injurious falls, which were made more likely with high fall-risk increasing drug (FRID) burden, in adults with chronic obstructive pulmonary disease (COPD) near end of life.1 “Fall-risk increasing drugs are commonly prescribed to people with COPD … Read more
Chia-Chih Kuo, APN Credit: ResearchGate Treatment with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) is associated with better long-term liver outcomes than sodium-glucose cotransporter-2 inhibitors (SGLT2is) in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) and type 2 diabetes (T2D), according to findings from a recent study.1 Leveraging data for more than 150,000 patients from the … Read more
New research has yielded an updated definition of hyperfiltration to address age-related renal function decline in kidney donor candidates with obesity and glucose tolerance disorder.1 The revised formula uses both age and glomerular filtration rate (GFR) without body surface area correction to determine the threshold value for hyperfiltration, overcoming inherent limitations of the conventional method … Read more