National Trends in Preventive Aspirin Use Shaped by ASCVD Risk

Archyde A shift in Coronary Prevention: Declining Aspirin Use Among High-Risk Individuals new research sheds light on a concerning trend in the use of aspirin for preventing cardiovascular disease. While aspirin has long been a go-to medication for mitigating heart attack adn stroke risk, recent findings suggest a downward trend in its usage, especially among … Read more

National Trends in Preventive Aspirin Use Shaped by ASCVD Risk

Timothy S. Anderson, MD Credit: University of Pittsburgh An analysis of preventive aspirin trends by atherosclerotic cardiovascular disease (ASCVD) risk revealed that self-reported primary prevention aspirin use decreased among older adults and adults with low ASCVD risk, but additionally among adults with higher ASCVD risk.1 Evidence-based recommendations released by the American College of Cardiology/American Heart … Read more

Patient Factors Influence Semaglutide Initiation After Obesity Diagnosis

Andrew C. Stokes, PhD Credit: Boston University Patient factors, including sociodemographic, healthcare, and clinical elements, were linked to the initiation of semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1 RA), in a population with obesity without type 2 diabetes (T2D).1 Among more than 97,000 commercially insured adults in a recent cohort study, approximately 2.0% began semaglutide … Read more

JAKi Treatment for Psoriatic Arthritis Not Associated With Increased CVD, VTE, Cancer Risk

Sizheng Steven Zhao, MBChB, PhD Credit: LinkedIn JAK inhibitor (JAKi) therapy was not associated with an increased risk of cardiovascular disease, venous thromboembolism (VTE), or some cancers in people with psoriatic arthritis (PsA) and spondyloarthritis (SpA) compared to TNF inhibitors (TNFi) or IL-17 inhibitors (IL-17i).1 “Compared to TNFi, tofacitinib was shown to increase risk of … Read more

Higher Life’s Essential 8 Score for Cardiovascular Health Linked to Reduced MASLD Risk

New research is providing clinicians with an overview of the association between cardiovascular health and the risk of developing metabolic dysfunctional-associated steatotic liver disease (MASLD).1 Leveraging National Health and Nutrition Examination Survey (NHANES) 2017-March 2020 data and using the American Heart Association (AHA)’s Life’s Essential 8 (LE8) score as a benchmark of cardiovascular health, investigators … Read more

Pegloticase Does Not Increase Risk of CV/TE Events in People With Gout

Orrin M. Troum, MD, Credit: University of Southern California Pegloticase (Krystexxa; Amgen) was not found to put patients with gout at a higher risk of thromboembolic (TE) and cardiovascular (CV) events, according to a new post-hoc analysis of multiple trials assessing the therapy.1 “In these trials, the proportion of patients experiencing gout flares increased during … Read more

New Research on IgA Nephropathy and Nephrotic Syndrome: Differences in Clinical Features and Long-Term Prognosis

Unveiling the Unique Pathologies of IgA Nephropathy and Nephrotic Syndrome New research is shedding light on notable differences in the clinicopathological characteristics and long-term prognosis of patients with… The post New Research on IgA Nephropathy and Nephrotic Syndrome: Differences in Clinical Features and Long-Term Prognosis appeared first on NewsyList. Source link

Study Describes Clinical Features, Prognosis of Patients with IgAN, Nephrotic Syndrome

New research is shedding light on notable differences in the clinicopathological characteristics and long-term prognosis of patients with IgA nephropathy (IgAN) and nephrotic syndrome (NS) across different pathological phenotypes.1 Study findings suggest differences in the clinical features and renal prognosis of patients with IgAN-NS and minimal change disease (MCD), membranous nephropathy (MN), membranoproliferative glomerulonephritis (IgAN-MPGN), … Read more

Exploring Duloxetine for Depression in COPD: A Pilot Study

Abebaw Yohannes, MSc, PhDCredit: American Lung Association Prevalence of depression: Chronic obstructive pulmonary disease (COPD) is a major cause of disability, morbidity, and premature mortality.1,2 Approximately, two-thirds of COPD patients live with 2 or more comorbidities.4,5 Of these, over 40% suffer from co-morbid depression that warrants medical intervention; however, many remain undiagnosed and thus untreated.6 … Read more

Lean Steatotic Liver Disease Affects 12% of US Adults, Study Finds

Donghee Kim, MD, PhD Credit: Stanford Medicine New research is providing insight into the prevalence of lean steatotic liver disease (SLD) in the US, addressing potential changes in previous estimates following a 2023 change in liver disease nomenclature.1 Leveraging National Health and Nutrition Examination Survey (NHANES) data from 2017-2023, investigators determined the age-adjusted prevalence of … Read more