Monocyte-to-HDL-C Ratio Correlated With Gout Risk and Renal Injury

Monocyte-to-HDL-C ratio (MHR) was found to be correlated with gout risk and renal dysfunction severity in a new cross-sectional study.1 “High monocyte counts and low HDL-C levels positively correlate with inflammation, and the MHR is recognized as a potential marker for inflammation and oxidative stress. The strong association between MHR and hyperuricemia suggests its utility … Read more

Aquatic Exercise Improves Physical, Psychosocial Outcomes in People With ME/CFS

Suzanne Broadbent, PhD Credit: University of the Sunshine Coast A self-paced aquatic exercise program improved physical and psychosocial outcomes in people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), according to new findings from a randomized controlled trial (RCT).1 “Appropriate modes of physical activity are uncertain, given the risk of symptom exacerbation, yet remaining sedentary may also … Read more

Equipping Clinicians to Navigate Social Determinants of Health

Mindy Hoang, MD Credit: Linkedin Some of the largest determinants of health are social and include factors like housing, food access, income, and immigration status. These factors limit the benefits that medical treatment can offer, especially in under-resourced settings, proving a frustration for many clinicians. Clinicians at Wayne State University in Detroit recognized that understanding … Read more

Opioid-Sparing Regimens Show Promise in Hospital Pain Management

Angel Goenawan, MD Credit: Linkedin The opioid crisis has forced clinicians to reassess how they approach pain management, particularly in hospital settings, where acute pain is frequent and the urgency to control it can result in opioid overuse. Emerging evidence suggests that non-opioid regimens, using medications such as acetaminophen, NSAIDs, gabapentin, and select antidepressants, can … Read more

Combination of Statins, Ezetimibe Could Prevent Thousands of Heart Attacks

Margret Leósdóttir, MD, PhD Credit: Åsa Hansdotter Treating patients hospitalized with myocardial infarction (MI) with a lipid-lowering therapy (LLT) combination of statins and ezetimibe could prevent thousands of further cardiovascular events, according to new research from Lund University and Imperial College London.1 Cardiovascular disease (CVD) is statistically the most common cause of death globally, with … Read more

Selective Vidian Neurectomy Plus FESS Shows Long-Term Relief in Nasal Itching

Credit: Adobe Stock/ eddows A new study found that 3 years of functional endoscopic sinus surgery (FESS) combined with selective vidian neurectomy improved nasal symptoms in patients with allergic rhinitis, chronic rhinosinusitis with nasal polyps (CRSwNP), and asthma.1 “Both groups demonstrated significant symptom improvement and enhanced quality of life three years post-surgery,” wrote investigators, led … Read more

Besifovir Improves Renal, Bone Health in HBV Patients Receiving Long-Term TDF

Hyung Joon Yim Credit: KU Medicine New research suggests switching to besifovir dipivoxil maleate (BSV) therapy may improve renal and bone health in patients with chronic hepatitis B virus (HBV) previously receiving long-term tenofovir disoproxil fumarate (TDF) treatment.1 The randomized, open-label, active-controlled, non-inferiority phase 4 clinical trial found switching to a 48-week BSV therapy regimen … Read more

Top News for Healthcare Providers from the Week of 04/06

Welcome to The HCPFive, your go-to roundup for the latest healthcare news and breakthroughs, curated specifically for busy healthcare professionals. Each week, we highlight 5 key developments or headlines from healthcare that you need to know—whether it’s a cutting-edge treatment, regulatory updates, or innovations shaping the future of medicine. This week’s top stories included new … Read more

Mortality Risk Rises 2.7-Fold in Adults After Respiratory Syncytial Virus

Maria João Fonseca, PhD | Image Credit: Linkedin Presented at the European Society of Clinical Microbiology and Infectious Disease (ESCMID) Global 2025 Congress, a recent study from Denmark indicated that adults suffering from respiratory syncytial virus-associated acute respiratory infection (RSV-ARI) have a risk of mortality 2.7-fold higher than that of a healthy person.1,2 RSV-ARI refers … Read more

ACP Issues Best Practice Advice for Marijuana Use in Chronic, Noncancer Pain

Isaac Opole, MD, PhDCredit: UCI School of Medicine The American College of Physicians (ACP) has announced new Best Practice Advice for use of cannabis or cannabinoids for managing chronic, noncancer pain. Published during the ACP Internal Medicine (IM) Meeting 2025, the document is intended to inform clinicians whose patients are considering cannabis or cannabinoids on … Read more