TOPLINE: Sarcopenia, a hallmark of cancer cachexia, is associated with poor outcomes in chimeric antigen receptor (CAR) T-cell therapy, which can exacerbate muscle loss through inflammatory responses. The relationship between CAR T-cell therapy, sarcopenia, and metabolism requires further investigation to improve patient outcomes. METHODOLOGY: Researchers measured skeletal muscle index from clinical images in 83 patients … Read more
The same biological processes that drive aging — such as energy loss — may also contribute to lung diseases like chronic obstructive pulmonary disease (COPD). Cleveland Clinic researchers have developed a metabolic age clock that evaluates an individual’s metabolic function relative to the expected norm for their age group. Using this tool, they identified a … Read more
Consumption of sugary drinks is linked to 9.8% of new cases of type 2 diabetes (T2D) annually, contributing to approximately 2.2 million cases worldwide. These beverages are also linked to 1.2 million new cardiovascular disease (CVD) cases each year, or 3.1% of the global total, according to a study published in Nature Medicine. The researchers analyzed … Read more