Azvudine beats paxlovid in reducing COVID-19 deaths

A large-scale study reveals azvudine’s comparable efficacy to Paxlovid, fewer adverse effects, and potential antitumor benefits in patients with liver cancer.

medical practitioner wearing blue surgical latex gloves holding yellow drugs packet.Study: Real‐world effectiveness and safety of oral azvudine versus nirmatrelvir‒ritonavir (Paxlovid) in hospitalized patients with COVID-19: a multicenter, retrospective, cohort study. Image Credit: Cryptographer/Shutterstock.com

In a recent study published in the Signal Transduction and Targeted Therapy, a group of researchers compared the effectiveness and safety of azvudine versus nirmatrelvir-ritonavir (Paxlovid) in hospitalized coronavirus disease 2019 (COVID-19) patients, with a focus on clinical outcomes, adverse events (AEs), and potential benefits for patients with malignant tumors.

Background

Since the outbreak of COVID-19 in…

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