A new study, jointly led by Liverpool School of Tropical Medicine and the Centre for Research in Infectious Diseases (CRID) in Cameroon, has detected a DNA marker in a gene encoding for a key enzyme, known as cytochrome P450, that helps mosquitoes to break down and survive exposure to pyrethroids, the main insecticides used for treating bed nets.
This new finding, published in Science Translational Medicine, will help to better implement insecticide resistance management strategies and contribute to reducing the burden of malaria in sub-Saharan Africa, home to 90% of cases globally.
Our study designed field-applicable tools to easily track the spread of metabolic resistance in the major malaria mosquito species and assess its impact on control interventions. These important findings can help to…