For decades, multiple sclerosis research has focused on myelin, the insulation around the brain’s wiring. Scientists paid less attention to another loss that was happening in parallel: neurons in the cortex, the seat of higher thinking and cognition, were quietly dying. A team led by UC San Francisco, University of Cambridge, and Cedars-Sinai Medical Center … Read more
A common wild plant may hold hidden brain benefits. Dandelion leaf polyphenols survive digestion and continue targeting pathways associated with Alzheimer’s disease. Study: Characterisation of Dandelion Polyphenols and Their In Vitro Neuroprotective Effects During Simulated Digestion. Image credit: DUSAN ZIDAR/Shutterstock.com A recent study in Foods examined the enzyme-targeted neuroprotective potential of polyphenols from dandelion flowers, roots, … Read more
A novel engineered microbial system transforms discarded plastic into a frontline Parkinson’s treatment, offering a glimpse into a future where waste becomes medicine. Study: Microbial upcycling of plastic waste to levodopa. Image Credit: jmcatholic / Shutterstock In a recent study published in the journal Nature Sustainability, researchers demonstrate the successful engineering of a biological process to … Read more
After a heart attack, cardiologists can reopen blocked vessels and restore blood flow, but the muscle cells that died will never be replaced. “The heart is one of the organs with the least ability to regenerate,” said Ke Cheng, Alan L. Kaganov Professor of Biomedical Engineering at Columbia Engineering. “The spontaneous regeneration power is very, very limited.” In … Read more
A topical cream activated the skin’s immune defenses and suppressed tumor growth in two preclinical models of cutaneous squamous cell carcinoma (cSCC), one of the most common cancers in the world, according to a study published today in the Journal of Clinical Investigation. Developed by researchers at the Perelman School of Medicine at the University … Read more
Researchers at the University of California San Diego have uncovered how a single protein triggers two opposite responses in blood vessels – one inflammatory and one protective. This protein, a cell-surface receptor called protease-activated receptor-1 (PAR1), plays a critical role in maintaining the structural integrity of our blood vessels. Understanding how PAR1 switches between healing … Read more
New research suggests that zinc does far more than support immunity, revealing intricate molecular switches that may influence how the heart responds to inflammatory injury. Review: Zinc: A metallic shield against cardiac inflammation. Image Credit: Cagkan Sayin / Shutterstock In a recent review published in the journal Metallomics, researchers synthesized a broad body of mechanistic and … Read more
The brain’s ability to carry out everything from forming memories to coordinating movement depends on its cells producing the right proteins at the right time. But directly measuring this protein production, known as translation, across different types of brain cells has been a challenge. Now, scientists at Scripps Research and UC San Diego have developed … Read more
Archyde The Hidden Risks of Everyday Relief: How Prolonged PPI Use Could Be Undermining Your Health For millions, medications like omeprazole, pantoprazole, and esomeprazole are a go-to solution for heartburn, acid… You can read the full story here: Omeprazole & Mineral Loss: Long-Term Use Risks. Source link
A new study, jointly led by Liverpool School of Tropical Medicine and the Centre for Research in Infectious Diseases (CRID) in Cameroon, has detected a DNA marker in a gene encoding for a key enzyme, known as cytochrome P450, that helps mosquitoes to break down and survive exposure to pyrethroids, the main insecticides used for … Read more