The Weight of Two Worlds: Lipo-Lymphedema and Obesity

When Shannon Ashley, now 43 years old, was in her tweens and teens, her legs were noticeably large. Shannon Ashley “Once I hit 12, my calves were unusually large, like tree trunks,” Ashley said. She tried to hide her outsized lower extremities, a contrast to her slender upper body, beneath wide-leg pants, and the size … Read more

Consider Spice Testing in Vulvar Dermatitis Complaints

TOPLINE: In patients with chronic vulvar complaints, allergic contact dermatitis (ACD) shows high prevalence with 86.6% exhibiting positive patch test reactions, of which 37.9% were clinically relevant. Nearly half of patients (43.3%) had reactions to spices and herbs, with 34.5% having clinically relevant reactions. METHODOLOGY: Researchers conducted a retrospective analysis of 67 adult patients with … Read more

Breast-Conserving Tx, Mastectomy Have Similar Outcomes

TOPLINE: In a multicenter cohort study of 575 South Korean patients with BRCA1 or BRCA2 pathogenic variants, breast-conserving treatment demonstrated comparable oncologic outcomes to mastectomy over a median follow-up of 8.3 years. After propensity score matching, no significant differences between the two surgical approaches were found in terms of locoregional recurrence, distant recurrence, and overall … Read more

Axolotl Shows Promise in Unlocking Skin Regeneration Secrets

For over 200 years, researchers have been captivated by axolotl salamanders (Ambystoma mexicanum) and their remarkable regenerative abilities, seeking to uncover secrets that could revolutionize regenerative medicine, including the scarless healing of wounds. “The axolotl salamander is the most studied animal ever in science for its neotenic ability to regenerate,” Jill S. Waibel, MD, dermatologist … Read more