Blood-based test could personalize treatment for patients with HPV-associated throat cancer

Researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) are advancing the understanding of a promising blood test that could personalize treatment and surveillance for patients with human papillomavirus (HPV)-associated throat cancer. The research, published in JAMA Otolaryngology – Head … Read more

Lipid nanoparticles help CAR T cells melt pancreatic cancer barriers

Often diagnosed when surgery is no longer an option, pancreatic cancer is one of the most difficult cancers to treat and has one of the lowest rates of survival among major malignancies. Like many solid tumors, the most common type of pancreatic cancer, pancreatic ductal adenocarcinoma (PDAC), is shielded by the desmoplastic matrix-a dense barrier … Read more

Transcatheter valve-in-valve procedure improves short-term outcomes in high-risk patients

In patients with a poorly functioning bioprosthetic mitral valve in the heart, a minimally invasive procedure to insert a new valve was associated with a lower rate of death or disabling stroke within one year, compared with patients who underwent standard repeat mitral valve replacement surgery, according to a study presented at the American College … Read more

Advanced endoscopic technique successfully treats early-stage colorectal cancer

In the months before his wedding, Queens resident Roberto Pineda Sanchez noticed persistent rectal bleeding, a dangerous symptom he almost ignored. Thankfully, he decided to bring it up to his doctor—a potentially lifesaving choice that led to his swift and successful treatment for colorectal cancer. “He said it’s probably a hemorrhoid or fissure or something … Read more

GLP-1 medications show mixed effects on body contouring outcomes

For patients undergoing body contouring surgery to remove excess abdominal skin after massive weight loss, use of GLP-1 weight-loss medications may have mixed effects on complication risks, suggests a study in the April issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer. “As GLP-1 receptor agonist [GLP1ra] medications become increasingly integrated into the care … Read more

‘An AI physiotherapist helped diagnose a rare medical emergency and saved me from paralysis’

A 47-year-old Cambridgeshire woman has described the “unbearable pain” she experienced – to the point she wished somebody would cut her “leg off” – before she got a rare diagnosis that affects up to three in 100,000 people via an AI physiotherapist. Amie Smith, a carer, said she first felt lower back pain on Sunday … Read more

New mechanism driving glioblastoma growth offers potential treatment targets

Australian researchers have uncovered a critical mechanism driving the growth and spread of glioblastoma – one of the most aggressive and lethal forms of brain cancer – potentially paving the way for more effective treatments. In a new study led by Adelaide University scientists from the Centre for Cancer Biology (CCB), researchers identified a previously … Read more

Digital decision support tool improves outcomes in colorectal surgery

Research published in The Lancet Gastroenterology & Hepatology provides robust evidence for the use of a digital visualization and decision support tool in colorectal (bowel) surgery. This is the first time that a digital decision support tool has been conclusively proven to significantly improve outcomes in this type of surgery. Colorectal cancer is the third … Read more

Women welcome MOH move to screen for family cancer history, have insurance cover preventive surgery

SINGAPORE – Business executive Ann, 51, was diagnosed with Stage 1 breast cancer in her right breast. But when she opted for a double mastectomy in 2021 at age 47 and had both breasts removed at the same time, her insurers refused to cover the preventive surgery to remove and reconstruct her non-cancerous left breast. … Read more

Exertional dyspnoea points to an unexpected diagnosis

This article has been allocated 0.5 EA by the RACGP and ACRRM for the 2026-2028 triennium. You can self-report this CPD/PDP activity by logging it online with the RACGP and ACRRM. Click on the link for RACGP Quick Log or go to your ACRRM page. Leo is a 62-year-old aeroplane engineer who presents with a three-month history of … Read more