The effects of spinal cord injuries are complex and multifaceted. People lose not only the ability to control the movement of their limbs, but also the ability to receive sensory feedback from them. Both are critical to generate the coordinated movement involved in walking. Now, a team of researchers from Brown University, Rhode Island Hospital, … Read more
Summary: Spinal cord injuries have long been considered permanent because neurons in the central nervous system lack the natural ability to regrow. However, researchershave developed a novel, 3D-printed implant that could change that. The study details a multifunctional scaffold designed to mimic the spinal cord’s physical structure while delivering tiny RNA-loaded particles. These particles “silence” … Read more
Researchers from RCSI University of Medicine and Health Sciences have developed a novel implant that delivers tiny growth-promoting particles directly to injured nerve cells, helping them to regrow after spinal cord injury. The study, published in the journal Bioactive Materials, shows how a 3D implant designed to mimic the structure and stiffness of the spinal … Read more
In a new clinical study, researchers from the Texas Biomedical Device Center (TxBDC) at The University of Texas at Dallas demonstrated unprecedented rates of recovery for spinal cord injuries. In this study, published in the prestigious journal Nature on May 21, individuals with incomplete spinal cord injury safely received a combination of stimulation of a nerve in the neck … Read more
A modified herpes virus that targets spinal cord nerve cells to treat neurogenic bladder in people with spinal cord injury is underway in a first-in-human clinical trial by UTHealth Houston at TIRR Memorial Hermann. Neurogenic bladder, also called neurogenic lower urinary tract dysfunction, often occurs after a spinal cord injury. The spinal cord helps coordinate bladder storage and voiding. … Read more
For over 200 years, researchers have been captivated by axolotl salamanders (Ambystoma mexicanum) and their remarkable regenerative abilities, seeking to uncover secrets that could revolutionize regenerative medicine, including the scarless healing of wounds. “The axolotl salamander is the most studied animal ever in science for its neotenic ability to regenerate,” Jill S. Waibel, MD, dermatologist … Read more
The latest study results have been published online in the renowned “The Lancet Neurology” journal. A multi-centre clinical trial (NISCI trial: Nogo-A Inhibition in acute Spinal Cord Injury Study) investigated the antibody NG 101 (anti-Nogo-A), which blocks and thus neutralizes the body’s own Nogo-A protein. Several international studies in animal models have shown that this … Read more