Researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) are advancing the understanding of a promising blood test that could personalize treatment and surveillance for patients with human papillomavirus (HPV)-associated throat cancer. The research, published in JAMA Otolaryngology – Head … Read more
Often diagnosed when surgery is no longer an option, pancreatic cancer is one of the most difficult cancers to treat and has one of the lowest rates of survival among major malignancies. Like many solid tumors, the most common type of pancreatic cancer, pancreatic ductal adenocarcinoma (PDAC), is shielded by the desmoplastic matrix-a dense barrier … Read more
Even after inflammation resolves, colonic stem cells can retain a hidden molecular memory that increases the likelihood of later tumour growth, offering a new mechanistic link between chronic inflammatory disease and cancer risk. Study: Epigenetic memory of colitis promotes tumour growth. Image Credit: Antonio Marca / Shutterstock In a recent study published in the journal Nature, … Read more
Advanced gastric cancer remains one of the deadliest malignancies, with a 5-year overall survival rate below 10%. In recent years, combining chemotherapy with PD-1 or PD-L1 inhibitors has become standard first-line care for previously untreated HER2-negative disease. Yet major global trials and subgroup analyses have pointed to a recurring pattern: Asian patients often experience stronger … Read more
In aggressive lymphomas, inflammatory messengers reprogram the “conductors” of the immune system, causing lymph nodes structure to collapse. A team led by Simon Haas describes in “Nature Cancer” this process for the first time using single-cell and spatial analyses. Lymph nodes are highly organized command centers of the immune system. Within these structures, immune cells … Read more
Metastasis, the spread of cancer from a primary tumor to other parts of the body, is difficult to study in the lab, in part because researchers lack reliable ways to recreate the conditions cancer cells encounter as they travel through the bloodstream. Rice University bioengineers report a new platform designed to streamline one of the … Read more
People with a healthy thymus gland live longer and are less likely to fall ill. In addition, immunotherapies are more often successful in patients with a healthy thymus. This is shown by two international studies involving Universitätsmedizin Frankfurt. The results, now published in the journal Nature, open up new approaches to maintaining health during the … Read more
A team of researchers at Baylor College of Medicine, St. Jude Children’s Research Hospital, Texas Children’s Hospital, and collaborating institutions reveals in the journal Nature a novel mechanism that drives the development of pediatric supratentorial ependymoma (EPN), the third most common pediatric brain tumor. The findings suggest potential new approaches to treat these aggressive and … Read more
An international team led by researchers at Baylor College of Medicine, Texas Children’s Hospital, McGill University and University of Pittsburgh School of Medicine has discovered what drives the growth of a lethal pediatric brain tumor called Posterior Fossa Type A (PFA) ependymoma. The researchers report in the journal Nature that androgens, commonly known as male … Read more
From blood sugar control to immune and gut effects, camel milk is drawing scientific interest as a functional food, but this review says any promise must be weighed against the real safety risks of drinking it raw. Review: Camel Milk as a Functional Food: Nutritional Composition, Health-Promoting Benefits, and Safety Considerations. Image Credit: MehmetO / … Read more