Angiology

Increased prevalence and risk of atherosclerotic cardiovascular disease in individuals with Type 1 diabetes and metabolic dysfunction-associated steatotic liver disease | Cardiovascular Diabetology

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Van der Schueren B, Ellis D, Faradji RN, Al-Ozairi E, Rosen J, Mathieu C. Obesity in people living with type 1 diabetes. Lancet Diabetes Endocrinol. 2021;9(11):776–85. PubMed  Google Scholar  Bielka W, Przezak A, Molęda P, Pius-Sadowska E, Machaliński B. Double diabetes-when type 1 diabetes meets type 2 diabetes: definition, pathogenesis and recognition. Cardiovasc Diabetol. 2024;23(1):62. … Read more

Impact of sodium–glucose transport protein-2 (SGLT2) inhibitors on the inflammasome pathway in acute myocardial infarction in type 2 diabetes mellitus: a comprehensive review | Cardiovascular Diabetology

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Yang L, Zhang X, Wang Q. Effects and mechanisms of SGLT2 inhibitors on the NLRP3 inflammasome, with a focus on atherosclerosis. Front Endocrinol (Lausanne). 2022;13:992937. PubMed  Google Scholar  Kim SR, Lee SG, Kim SH, Kim JH, Choi E, Cho W, et al. SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with … Read more

Metabolic profiling of frailty, associations with type 2 diabetes and interaction with genetic susceptibility | Cardiovascular Diabetology

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Study population Detailed information of the study design has been presented previously [15]. Briefly, the UK Biobank enrolled over 0.5 million participants aged 37 to 73 years from 22 sites across the UK between 2006 and 2010, and collected extensive information at recruitment, including data from touchscreen questionnaires, physical examinations, biological samples, and longitudinal follow-up for … Read more

Sacubitril/Valsartan attenuates progression of diabetic cardiomyopathy through immunomodulation properties: an opportunity to prevent progressive disease | Cardiovascular Diabetology

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Neprilysin activity in clinical pre-heart failure Activity of NEP enzyme, the primary target of Sacubitril, was quantified in plasma of a sub-cohort of pre-HFpEF patients with DM from the PARABLE trial [15] (n = 60/250) to understand impact of Sacubitril/Valsartan in this specific population. Type 2 DM patients (n = 44/60) showed positive correlation between plasma NEP activity at … Read more

Predictors of pre-hospital delay among stroke patients in Yekatit-12 hospital Addis Ababa, Ethiopia: unmatched case-control study | International Journal of Emergency Medicine

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Study design and study area The study was conducted at Yekatit 12 Hospital Medical College, which is among the six regional hospitals in Addis Ababa, Ethiopia. The hospital provides service for more than 3,000,000 people living in its catchment area. A retrospective unmatched case-control study design was adopted at the hospital for acute stroke patients … Read more

Combined effect of skeletal muscle mass loss and elevated insulin resistance on heart failure risk in older adults: a community-based longitudinal cohort study | Cardiovascular Diabetology

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Tomasoni D, Adamo M, Lombardi CM, Metra M. Highlights in heart failure. ESC Heart Fail. 2019;6(6):1105–27. https://doi.org/10.1002/ehf2.12555. Article  PubMed  Google Scholar  GBD 2017 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and National incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis … Read more

Temporal prevalence and prognostic impact of diabetes mellitus and albuminuria in heart failure with preserved ejection fraction | Cardiovascular Diabetology

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Savarese G, Becher PM, Lund LH, Seferovic P, Rosano GMC, Coats AJS. Global burden of heart failure: a comprehensive and updated review of epidemiology. Cardiovasc Res. 2022;118:3272–87. CAS  Google Scholar  Packer M, Lam CSP, Lund LH, Maurer MS, Borlaug BA. Characterization of the inflammatory-metabolic phenotype of heart failure with a preserved ejection fraction: a hypothesis … Read more

Joint association of estimated glucose disposal rate and systemic inflammation response index with mortality in cardiovascular-kidney-metabolic syndrome stage 0–3: a nationwide prospective cohort study | Cardiovascular Diabetology

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Study design and population The National Health and Nutrition Examination Survey (NHANES), conducted by the Centers for Disease Control and Prevention (CDC) in the United States, is a comprehensive, stratified, multi-stage probability sample survey that represents the nation’s population. It is performed every two years to evaluate the health and nutritional status of residents in … Read more

Association between C-reactive protein-triglyceride glucose index and stroke risk in different glycemic status: insights from the China Health and Retirement Longitudinal Study (CHARLS) | Cardiovascular Diabetology

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Feigin VL, Stark BA, Johnson CO, Roth GA, Bisignano C, Abady GG, Abbasifard M, Abbasi-Kangevari M, Abd-Allah F, Abedi V, Abualhasan A. Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the global burden of disease study 2019. Lancet Neurol. 2021;20(10):795–820. CAS  Google Scholar  Ma Q, Li R, … Read more

Exploring the impact of metabolic comorbidities on epicardial adipose tissue in heart failure with preserved ejection fraction | Cardiovascular Diabetology

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Baseline characteristics of the Belgian cohort A total of 104 consecutive HFpEF patients (stage C) (77 ± 8 years; 55% female), 16 pre-HF patients (stage B) (75 ± 4 years; 62% female), and 26 age- and sex-matched controls (76 ± 5 years; 63% female) were prospectively included in the study. Baseline patient characteristics are summarized in Table 1. Compared to controls, HFpEF patients had a higher … Read more