Fiber supplement stabilizes blood sugar in gestational diabetes

A simple fiber supplement could reshape the gut microbiome, stabilize blood sugar spikes, and even prevent preterm births in high-risk pregnancies, offering a promising new path for precision prenatal care.  Study: Dietary fiber supplementation mitigates gestational diabetes risk and preterm birth via gut microbiota modulation: a randomized controlled trial. Image credit: dilyaz/Shutterstock.com A new study … Read more

New algorithm enables precise subtyping of metabolic liver disease

Metabolic-associated steatotic liver disease (MASLD) is a clinically heterogeneous condition with highly variable outcomes affecting more than 30% individuals globally. The disease is conventionally staged by histological progression, ranging from simple steatosis to metabolic dysfunction-associated steatohepatitis (MASH) and ultimately fibrosis or cirrhosis. Beyond liver-related outcomes, MASLD significantly elevates the risk of extrahepatic complications, including cardiovascular … Read more

Patients who stop GLP-1 drugs often restart or try alternatives

A large real-world study shows that patients who stop popular GLP-1–based weight-loss drugs often return to treatment or try alternative therapies, helping explain why average weight regain after discontinuation may be smaller than expected. Study: Obesity Treatments and Weight Changes in Clinical Practice After Discontinuation of Semaglutide or Tirzepatide. Image credit: KaterynaBorodina/Shutterstock.com Obesity treatment has … Read more

Physical function metrics improve mortality prediction in elderly heart failure patients

Current models of mortality risk after heart failure (HF) rely primarily on cardiac-specific clinical variables and may underestimate risk in elderly East Asian patients. Researchers from Japan used machine learning to analyze data from a nationwide registry of elderly HF patients. Their new model includes metrics of physical function and improved risk reclassification by about … Read more

Syzygium jambolanum extract shows promise for diabetes management

The search for effective and accessible therapies for diabetes continues to draw attention to medicinal plants with a long history of traditional use. A new study investigates the protective and antidiabetic effects of Syzygium jambolanum extracts, providing biochemical and clinical evidence supporting their role in improving glycaemic control and metabolic health. Traditional remedy under scientific … Read more

Can GLP-1 drugs slow neurodegeneration? New review finds promising signals but limited clinical proof

Emerging evidence suggests widely used metabolic drugs could influence brain aging pathways, yet large clinical trials are still needed to confirm whether they truly alter the course of neurodegenerative disease. Study: The promise of GLP-1 receptor agonists for neurodegenerative diseases. Image Credit: Antonio Marca / Shutterstock In a recent review published in the Journal of Clinical … Read more

Diabetic nephropathy shows severe biochemical abnormalities

Background and objectives Chronic diabetes mellitus is marked by hyperglycemia and metabolic dysfunction, increasing the risk of complications such as nephropathy. This study aimed to evaluate key biochemical parameters among participants with diabetic nephropathy (DNp), diabetes control (DC), nephropathy control (NC), and healthy control groups. Methods A prospective case-control study was conducted with 200 participants … Read more

PFAS exposure increases gestational diabetes risk

A comprehensive review of nearly 130 studies shows the strongest evidence to date that “forever chemicals” are associated with gestational diabetes, while underscoring uncertainty around other diabetes outcomes and the need for more prospective research. Study: Associations of perfluoroalkyl and polyfluoroalkyl substances with markers of glycaemic control, insulin secretion and sensitivity, and diabetes risk: a … Read more

Pregestational Diabetes & NICU Admissions

Key Points Infants⁤ born to mothers with pregestational diabetes face a higher risk of NICU admission. Research highlights teh importance⁣ of managing diabetes during pregnancy. Understanding risk factors can improve neonatal care and outcomes. New Study Links ⁣Pregestational ⁣Diabetes ‍to Increased NICU ⁤Admissions ‍ Updated May 22, 2025 A recent ​study published in the European … Read more

Large global study links higher alcohol intake to increased pancreatic cancer risk

Drinking more alcohol, especially beer or liquor, modestly raises your risk of pancreatic cancer, according to one of the world’s largest and most comprehensive studies. Study: Alcohol intake and pancreatic cancer risk: An analysis from 30 prospective studies across Asia, Australia, Europe, and North America. Image Credit: crystal light / Shutterstock The analysis of a large-scale dataset … Read more