Cancer vaccines are showing promise at last.

Cancer Vaccines: Coley’s Dream Coming True? Over a century ago, William Coley, an American surgeon, observed that infections sometimes caused tumors to shrink. This led him to develop a treatment using bacteria to trigger the immune system against cancer, a revolutionary idea at the time. Coley’s Insight: A Legacy for Cancer Research Coley’s pioneering work, … Read more

Immunocompromised adults show weaker response to RSV vaccines

Johns Hopkins Medicine researchers have shown that people 60 years or older with weakened immunity -; primarily organ transplant recipients who take immunosuppressive medications to reduce the risk of rejection and others with immune system disorders -; do not respond as strongly to vaccines against the respiratory syncytial virus (RSV) as people in the same … Read more

Nogo-A inhibition demonstrates potential for spinal cord injury recovery

The latest study results have been published online in the renowned “The Lancet Neurology” journal. A multi-centre clinical trial (NISCI trial: Nogo-A Inhibition in acute Spinal Cord Injury Study) investigated the antibody NG 101 (anti-Nogo-A), which blocks and thus neutralizes the body’s own Nogo-A protein. Several international studies in animal models have shown that this … Read more

Chronic gut infection may play role in Alzheimer’s disease progression

Arizona State University and Banner Alzheimer’s Institute researchers, along with their collaborators, have discovered a surprising link between a chronic gut infection caused by a common virus and the development of Alzheimer’s disease in a subset of people. It is believed most humans are exposed to this virus -; called cytomegalovirus or HCMV -; during the … Read more