When a rhinovirus, the most frequent cause of the common cold, infects the lining of our nasal passages, our cells work together to fight the virus by triggering an arsenal of antiviral defenses. In a paper publishing January 19 in the Cell Press journal Cell Press Blue, researchers demonstrate how the cells in our noses … Read more
Researchers at Mass General Brigham and Karolinska Institutet have identified a new method to predict asthma exacerbations with a high degree of accuracy. The study is published in Nature Communications. Asthma is one of the world’s most common chronic diseases, affecting over 500 million people. Asthma exacerbations – commonly known as asthma attacks – are … Read more
Announcing a new article publication for Cardiovascular Innovations and Applications journal. Asthma and cardiovascular diseases (CVDs) are intricately linked, because of their widespread prevalence and shared pathophysiological processes. People who have experienced overlapping asthma exacerbation, persistent asthma, or asthma-chronic obstructive pulmonary disease (COPD) face elevated CVD morbidity and mortality risks. These risks are exacerbated in … Read more
TOPLINE: Premature infants exposed to multiple courses of antibiotics around the time of birth had weaker lung function and a higher risk for asthma episodes by early school age than those with lower exposure. METHODOLOGY: The study analyzed 3820 premature infants born between 22 and 36 weeks of gestation with low birth weights (< 1500 … Read more
Prenatal exposure to different microplastic particles may impact the neonatal gut microbiome in a manner that increases individuals’ risk of asthma, new findings suggest, and this impact is transmissible through live microbiota. These results were presented at the American Thoracic Society (ATS) 2025 International Conference, with the poster being titled ‘Urban Air, Diesel Exhaust and … Read more
TOPLINE: Neonates born preterm with very low birth weight (VLBW) exposed to multiple perinatal antibiotics were at an increased risk for impaired lung function and asthma episodes at early school age, according to a new study. METHODOLOGY: This population-based, multicentre cohort analysis included 3820 neonates born preterm with VLBW (< 1500 g; median gestational age, … Read more
A fixed-dose triple-combination therapy of budesonide, glycopyrronium, and formoterol fumarate (BGF, Breztri Aerosphere; AstraZeneca) met all primary end points in a phase 3 Kalos (NCT04609878) and Logos trial (NCT04609904) among individuals with uncontrolled asthma, demonstrating improvement in lung function compared with dual-combination inhaled corticosteroid/long-acting beta2-agonist (ICS/LABA) medicines.1 Image credit: Goffkein | stock.adobe.com The inhaled triple-combination … Read more
Primary care providers are accustomed to talking with their patients about how diet and nutrition influence health conditions like diabetes and cardiovascular health. But their effect on lung health? “It’s not always at the forefront of our recommendations for lung health,” said Christina M. Eckhardt, MD, MS, a pulmonologist and assistant professor of medicine and … Read more
Michael A. Bernstein, MD, can’t contain his curiosity when he hears the common claim: This is the worst allergy season ever. “I feel like the current season is always said to be ‘the worst’ for allergies, but it’s difficult to know how bad any season is until it’s actually over,” said Bernstein, a pulmonologist at … Read more
A major German study finds that early repeated antibiotic use in very low-birth-weight infants can have lasting effects on lung health, highlighting the importance of antibiotic stewardship and preventive care for preterm children. Study: Perinatal Antibiotic Exposure and Respiratory Outcomes in Children Born Preterm. Image Credit: mi_viri / Shutterstock In a recent study published in JAMA Network … Read more