Single-cell analysis reveals key chondrocyte subpopulations in osteoarthritis

Chondrocytes are specialized cells that are essential for cartilage maintenance and repair, and their dysfunction is central to the development of joint diseases like osteoarthritis (OA). However, the cell heterogeneity of chondrocytes in human articular cartilage is still not well defined, which hinders understanding of the pathogenesis of OA. This research, published in the Genes … Read more

Teodoro, Japanese counterpart tour Luzon military bases

MANILA, Philippines — Defense Secretary Gilberto Teodoro Jr. toured Japanese Defense Minister Gen Nakatani around military bases and facilities in Luzon on Sunday, highlighting the growing ties between the two countries. “Minister Nakatani was given a briefing and [a] guided tour of the operational capabilities and ongoing defense initiatives at Basa Air Base [in Floridablanca, … Read more

Takumi-shaped DNA hydrogels show promise for targeted therapies

Hydrogels are polymeric materials with three-dimensional network structures containing large amounts of water. They serve as sustained-release drug delivery systems as they can encapsulate various bioactive substances, including drugs, antigens, and even cells. Hydrogels are better drug delivery alternatives than conventional systems, as they are more biocompatible, biodegradable, and easily administered as an injectable scaffold. … Read more