Research has found that aging improves cognitive and physical functions, challenging the notion that growing older leads to decline. The researchers at Yale University, US, reveal that nearly half of the older adults over 65 improved in cognitive and physical functions over time based on data from the Health and Retirement Study. Additionally, the 12-year … Read more
Summary: A new study suggests that SSRIs, commonly prescribed antidepressants, may reduce biological markers of Alzheimer’s disease. In a cohort of 191 individuals, AD patients on SSRIs had lower levels of plasma phosphorylated tau-181, a key indicator of disease severity. Brain scans also showed that SSRIs restored metabolic activity in the dorsal raphe nucleus (DRN), … Read more
Surkalim DL, Luo M, Eres R, Gebel K, van Buskirk J, Bauman A, Ding D. The prevalence of loneliness across 113 countries: systematic review and meta-analysis. BMJ. 2022;9:376. https://doi.org/10.1136/bmj-2021-067068. Article Google Scholar Alpass FM, Neville S. Loneliness, health and depression in older males. Aging Ment Health. 2003;7(3):212–6. https://doi.org/10.1080/1360786031000101193. Article CAS PubMed Google Scholar Hawkley LC, … Read more
New research suggests that today’s B12 guidelines might be outdated, as even “normal” levels could still harm brain function. Scientists warn that subtle cognitive decline linked to B12 insufficiency might affect more people than expected. Credit: SciTechDaily.com Your brain might not be getting enough B12 — even if your levels are considered “normal.” A new … Read more
Summary: Even when within the normal range, lower levels of vitamin B12 may contribute to cognitive decline, according to a new study. Researchers found that older adults with lower biologically active B12 had slower cognitive processing and more white matter lesions, despite meeting current nutritional requirements. These findings suggest that the definition of B12 deficiency … Read more
Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K. Frailty in elderly people. Lancet. 2013;381(9868):752–62. Article PubMed Google Scholar Hoogendijk EO, Afilalo J, Ensrud KE, Kowal P, Onder G, Fried LP. Frailty: implications for clinical practice and public health. Lancet. 2019;394(10206):1365–75. Article PubMed Google Scholar Dent E, Martin FC, Bergman H, Woo J, Romero-Ortuno … Read more
The Evolving Landscape of Cannabis and Cognition: What’s Next? Table of Contents The Evolving Landscape of Cannabis and Cognition: What’s Next? Unveiling the Brain’s Response to Cannabis Did You Know? Short-Term Effects and Long-Term Implications Pro Tip: Navigating the Complexities of Cannabis Use the Future of Cannabis Research FAQ Recent research has ignited a crucial … Read more
TOPLINE: Heavy lifetime cannabis use is linked to reduced brain activation during working memory tasks in young adults, while recent use is also associated with reduced activation during cognitive tasks, new research shows. METHODOLOGY: Researchers analyzed data collected between 2012 and 2015 from the Human Connectome Project. The cross-sectional study included more than 1000 young … Read more
UPV/EHU researchers found that activating cannabinoid receptors with WIN55.212-2 improved memory and restored brain systems in rodents with neurodegenerative conditions, offering hope for new treatments. However, further research is needed to develop commercially viable molecules for clinical trials. A study by the University of the Basque Country (UPV/EHU) demonstrates that the drug WIN55,212-2 protects the … Read more
Older adults are more likely to suffer attention difficulties when home temperatures fall outside 68–75 °F. This study highlights the need for climate-resilient housing policies to protect seniors’ cognitive health as global temperatures rise. Higher temperatures are linked to an increased risk of cognitive decline. A groundbreaking study has revealed a strong link between indoor … Read more