disease-modifying therapy; disease-modifying therapy (DMT)

AI Pen Accurately Diagnoses Early PD via Handwriting

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Biomedical engineers have developed an artificial intelligence (AI)–enhanced pen for personalized handwriting analysis to aid in the early diagnosis of Parkinson’s disease (PD).  In a small pilot study, the “diagnostic pen” accurately recorded handwriting signals, and neural network-assisted analysis successfully distinguished PD from non-PD handwriting with greater than 95% accuracy. “Further validation through large-scale human … Read more

Despite Early Promise GLP-1 Disappoints in Parkinson’s

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Treatment with the glucagon-like peptide 1 (GLP-1) receptor agonist exenatide had no disease-modifying effects on movement, symptom severity or brain imaging in patients with Parkinson’s disease (PD) enrolled in a phase 3 trial. “The results of this trial have been eagerly anticipated, and the negative results will be a major disappointment to patients affected by … Read more