Biomedical engineers have developed an artificial intelligence (AI)–enhanced pen for personalized handwriting analysis to aid in the early diagnosis of Parkinson’s disease (PD). In a small pilot study, the “diagnostic pen” accurately recorded handwriting signals, and neural network-assisted analysis successfully distinguished PD from non-PD handwriting with greater than 95% accuracy. “Further validation through large-scale human … Read more
WASHINGTON, DC — Age-related neurodegenerative disorders — motor neuron diseases, demyelinating diseases, Alzheimer’s disease, and other proteinopathies — are at an “inflection point,” said researcher Andrea R. Merchak, PhD, with a fuller understanding of disease pathophysiology but an overall dearth of effective disease-modifying treatments. And this, Merchak said at the Gut Microbiota for Health (GMFH) … Read more
TOPLINE: Difficulty distinguishing spoken words from background noise, called speech-in-noise hearing impairment, was associated with increased risk for Parkinson’s disease (PD), with a 57% elevation in risk per 10 dB increase in the speech reception threshold (SRT), a new study showed. METHODOLOGY: In the preregistered prospective cohort study, investigators analyzed data for more than 159,000 … Read more
Treatment with the glucagon-like peptide 1 (GLP-1) receptor agonist exenatide had no disease-modifying effects on movement, symptom severity or brain imaging in patients with Parkinson’s disease (PD) enrolled in a phase 3 trial. “The results of this trial have been eagerly anticipated, and the negative results will be a major disappointment to patients affected by … Read more