Baricitinib can effectively treat polymyalgia rheumatica (PMR) without the use of oral glucocorticoids, according to results from a small, randomized, double-blind, placebo-controlled study. Among the 18 patients randomly assigned to the oral Janus kinase (JAK) inhibitor baricitinib, 14 achieved a C-reactive protein PMR activity score (CRP PMR-AS) of 10 or less after 12 weeks of … Read more
TOPLINE: The use of valaciclovir as prophylaxis prevents herpes zoster (HZ) in patients with systemic lupus erythematosus (SLE) receiving anifrolumab treatment, with no cases of zoster reported during the follow-up period in patients receiving valaciclovir. METHODOLOGY: Anifrolumab, a human monoclonal antibody binding to type I interferon receptor subunit 1, increases the risk for HZ in … Read more
TOPLINE: Influenza vaccination demonstrates consistent effectiveness of approximately 50% across all severity levels in children, with higher protection observed in younger children (age, 6 months to 8 years) than in older ones (age, 9-17 years). METHODOLOGY: Researchers conducted a test-negative case-control study to evaluate the vaccine effectiveness (VE) against severe influenza in children across eight … Read more
Doxycycline postexposure prophylaxis (doxyPEP) has the potential to substantially reduce real-world population-level incidence of sexually transmitted infections (STIs), a study in JAMA Internal Medicine suggested. This conclusion was reached by Stephanie E. Cohen, MD, medical director of the San Francisco City Clinic, Department of Public Health in San Francisco, and colleagues after examining STI trends … Read more
he Indonesian Maritime Security Agency (Bakamla) has signed a contract for a patrol vessel provided through a grant from the Japan International Cooperation Agency (JICA) worth some 9 billion yen (US$57 billion). Bakamla chief Vice Adm. Irfansyah and Mitsubishi Shipbuilding Co., Ltd. chief executive officer Shin Ueda signed the agreement at a… Source link
fter a decade of supporting initiatives, the Young Southeast Asian Leaders Initiative (YSEALI) Seeds for the Future grant competition awarded up to US$15,000 to each of its 16 recipients to develop innovative projects this year. The grants, established in 2014 by the United States Mission to ASEAN, aim to support young leaders aged 18 to … Read more