Scientists have identified why some patients developed dangerous blood clots called vaccine-induced immune thrombocytopenia and thrombosis (VITT) after receiving certain COVID‑19 vaccines, or after natural adenovirus infection. RT’s Three Key Takeaways: Rare Immune Mutation Causes Dangerous Clots: A study published in the New England Journal of Medicine found that a specific antibody mutation (K31E) can … Read more
TOPLINE: Nearly 12% of individuals using preexposure prophylaxis (PrEP) for HIV prevention, were diagnosed with alcohol use disorder (AUD) within 6 months of initiating PrEP, whereas nearly 3% were diagnosed before initiation. Fewer than 9% of those diagnosed received any US Food and Drug Administration (FDA)–approved medication for AUD. METHODOLOGY: Researchers carried out a retrospective … Read more
TOPLINE: Four clinical organizations jointly released a clinical advisory with evidence-based nutrition and lifestyle interventions to enhance glucagon-like peptide 1 (GLP-1) treatment outcomes for obesity. METHODOLOGY: An expert group comprised of multiple clinical and research disciplines assessed the literature to identify pragmatic priorities for nutrition and other lifestyle interventions relevant to GLP-1 treatment for obesity. … Read more
Archyde Cannabis Use Surges among Older Adults in The U.S., Raising Concerns Among Experts Washington, D.C. – Recent data indicates a notable rise in cannabis use among older adults in the United States, especially in states where medical cannabis is legal. This trend has sparked concerns among researchers and healthcare professionals, who point to potential … Read more
Cannabis use in older adults is up, according to researchers who used a national survey database to study emergent patterns in older adult use of the substance. Their results were published online in JAMA Internal Medicine. After noting an upward trend in seniors using cannabis — from 1.0% in 2005 to 4.2% in 2018 — … Read more
Historically, the presence of HIV infection in a patient with end-stage organ failure has been considered an absolute contraindication for organ transplantation. However, advances in antiretroviral therapy have significantly improved life expectancy for people living with HIV to the extent that the condition is now generally managed as a chronic disease. At the same time, … Read more
On any given day, Andrea Braden, MD, must make quick clinical decisions about hospital patients who require emergency care. Her biggest challenge as a hospitalist is “the anxiety around never knowing what is going to come in the door that day,” said Braden, who is also an OB/GYN and lead clinical educator for TeamHealth in … Read more
With the explosive popularity of glucagon-like peptide 1 (GLP-1) agonists, physicians say a key avenue in treating obesity is being underutilized by many clinicians: First-generation anti-obesity medications (AOMs). “First-generation medications don’t get as much attention as the newer ones,” said Courtney Younglove, MD, an obesity specialist and founder of Heartland Weight Loss in Overland Park, … Read more
LOS ANGELES — The novel phosphodiesterase 10A (PDE10A) inhibitor known as CPL’36 (Celon Pharma) is effective and generally safe in acute exacerbations of schizophrenia, new research suggested. In a phase 2 trial of 189 patients with acute schizophrenia, compared with the placebo group, the groups receiving CPL’36 20 or 40 mg once daily both met … Read more
LOS ANGELES — Saffron may help treat sexual dysfunction related to selective serotonin reuptake inhibitors (SSRIs), new research suggests. Results of a preliminary new review found saffron, a spice derived from the flower of Crocus sativus, commonly known as the “saffron crocus,” reduced erectile dysfunction in men and boosted arousal in women. Jeremy Wolfe, MD … Read more