HIV infection

Fatal Human Rabies in an HIV-Infected Migrant Worker with Well-Controlled Viral Load — Zhejiang Province, China, January 2026

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In January 2026, a 53-year-old male migrant worker was diagnosed with fatal rabies in Zhejiang Province, China. The patient had a documented 10-year history of human immunodeficiency virus (HIV) infection and was receiving regular antiretroviral therapy with Biktarvy. At the time of hospital admission, laboratory testing on January 12 demonstrated effective virological … Read more

Don’t Forget These Infectious Disease Screenings

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For years, public health experts have encouraged primary care physicians (PCPs) to screen for infectious diseases as well as cancers, heart disease risk factors, diabetes, and more. Many assessments for risk-based infections such as hepatitis B (Hep B), hepatitis C (Hep C), HIV, and bacterial sexually transmitted infections (STIs) were convoluted and constantly changing, resulting … Read more

1 in 7 HIV PrEP Users Face Alcohol Use Disorder

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TOPLINE: Nearly 12% of individuals using preexposure prophylaxis (PrEP) for HIV prevention, were diagnosed with alcohol use disorder (AUD) within 6 months of initiating PrEP, whereas nearly 3% were diagnosed before initiation. Fewer than 9% of those diagnosed received any US Food and Drug Administration (FDA)–approved medication for AUD. METHODOLOGY: Researchers carried out a retrospective … Read more

Spain Nears Legal Shift on HIV-Positive Donors

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Historically, the presence of HIV infection in a patient with end-stage organ failure has been considered an absolute contraindication for organ transplantation. However, advances in antiretroviral therapy have significantly improved life expectancy for people living with HIV to the extent that the condition is now generally managed as a chronic disease. At the same time, … Read more

Inexpensive HIV Med Improves Vision in Diabetic Eye Disease

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TOPLINE: Oral lamivudine, an inflammasome inhibitor originally approved for suppressing HIV, was a relatively safe and effective treatment for improving visual acuity in adults with center-involving diabetic macular edema, a serious complication of diabetic retinopathy. METHODOLOGY: Researchers conducted a clinical trial to assess the effectiveness of oral lamivudine vs placebo in improving visual acuity in … Read more

HIV Medication Adherence Critical for Viral Suppression

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TOPLINE: A recent study found that antiretroviral therapy adherence below 90% was associated with significantly lower odds of viral suppression among women living with HIV. METHODOLOGY: Researchers analyzed data from community-based prospective cohort study including women living with HIV across British Columbia, Ontario, and Quebec between 2013 and 2018. Overall, 1187 participants (median age, 42 … Read more

Certain HIV Meds Linked to Reduced Alzheimer’s Risk

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TOPLINE: Use of nucleoside reverse transcriptase inhibitors (NRTIs), but not other medications for HIV, was associated with a significantly reduced risk for Alzheimer’s disease (AD) in an analysis of two national databases. NRTIs are antiretroviral drugs that block the activation of inflammasome. METHODOLOGY: This study included data of nearly 272,000 US individuals from two national … Read more

What’s Stalling PrEP’s Success in Europe’s HIV Fight – Medscape

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What’s Stalling PrEP’s Success in Europe’s HIV Fight  Medscape Source link

Europe Grapples With Rising Childhood TB

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Children under 15 account for 4.3% of all new and relapsed tuberculosis (TB) cases in the WHO European Region, which includes Europe and Central Asia, compared with 3.9% in 2022, a 10% increase. The finding was released this week in the 2025 Tuberculosis Surveillance and Monitoring Report. Veronica Cristea, MD The news has prompted urgent … Read more

Switching to Three-Drug Regimen Maintains HIV Suppression

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TOPLINE: Switching from a boosted protease inhibitor (bPI)–based regimen to bictegravir plus emtricitabine plus tenofovir alafenamide (B/F/TAF) maintained virological suppression over 48 weeks in patients with HIV who had preexisting resistance to nucleoside reverse transcriptase inhibitors (NRTIs), however with increased adverse events.  METHODOLOGY: This phase 4 trial assessed the safety and efficacy of switching from … Read more