Helix

DNA strand separation requires more force in crowded cellular environments

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By creating a more true-to-life representation of DNA’s environment, researchers at Northwestern University have discovered that strand separation – the essential process a “resting” double helix undergoes before it can initiate replication or make repairs – may take more mechanical force than the field previously believed. Most biochemistry labs that study DNA isolate it within a … Read more

Senolytics offer hope for more precise Alzheimer’s treatments

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A new research paper was published in Aging (Aging-US) on March 29, 2025, as the cover of Volume 17, Issue 3, titled “Differential senolytic inhibition of normal versus Aβ-associated cholinesterases: implications in aging and Alzheimer’s disease.” In this study, a research team from Dalhousie University, led by Sultan Darvesh, discovered that certain anti-aging compounds, known as senolytics, can block … Read more