Infant With Incurable Disease is First to Successfully Receive Personalized Gene Therapy Treatment

KJ with his parents and siblings after first-of-its-kind personalized gene editing therapy –Credit: Children’s Hospital of Philadelphia In a historic medical breakthrough, a child diagnosed with a rare genetic disorder has been successfully treated with a customized CRISPR gene editing therapy by a team at Children’s Hospital of Philadelphia and Penn Medicine. The infant, KJ, … Read more

Chatbot Helps Users Adopt a Low FODMAP Diet

SAN DIEGO — Low fermentable oligo-, di-, and monosaccharides and polyols (FODMAPs) dietary advice has been shown to be effective in easing bloating and abdominal pain, especially in patients with irritable bowel syndrome (IBS), but limited availability of dietitians makes delivering this advice challenging. Researchers from Thailand have successfully enlisted a chatbot to help. In … Read more

Quick Turn to Mechanical Thrombectomy Improves PE Outcomes

Patients with pulmonary embolism (PE) who were treated with mechanical thrombectomy (MT) within 12 hours of hospital admission had significantly better pulmonary outcomes than patients treated with mechanical thrombectomy more than 12 hours after admission, based on new data from the FLASH registry. The benefits of prompt treatment with MT for patients with high-risk PE … Read more

Exposure to Antibiotics Preterm May Affect Lung Function

TOPLINE: Premature infants exposed to multiple courses of antibiotics around the time of birth had weaker lung function and a higher risk for asthma episodes by early school age than those with lower exposure.  METHODOLOGY: The study analyzed 3820 premature infants born between 22 and 36 weeks of gestation with low birth weights (< 1500 … Read more

Hospitalists Lead Charge Against HAIs

It reads like the alphabet soup of healthcare: CDI, MRSA, CAUTI, and VAE. Those letters all fall under the category of hospital or healthcare-acquired infections (HAIs), and they can wreak havoc on patient care. On any given day, about 1 in 31 hospital patients has at least one HAI, according to the Centers for Disease … Read more

NJ Cancer Treatment: Morris Cancer Center Advances Care

A New Era in Cancer Care: Morris Cancer Center Opens in New Brunswick Table of Contents A New Era in Cancer Care: Morris Cancer Center Opens in New Brunswick A Collaborative Vision for Comprehensive Care State-of-the-Art Facility Details Accelerating Research and Innovation A Statewide Investment in Oncology The Growing Need for Specialized Cancer Care The … Read more

Acute Kidney Injury Tied to Poor Outcomes in Hospitals

TOPLINE: A substantial proportion of patients admitted to hospitals in Italy experienced acute kidney injury (AKI), which was associated with worsened in-hospital mortality outcomes, longer hospital stays, and more frequent admissions to intensive care units (ICUs). METHODOLOGY: Researchers conducted a retrospective observational study to examine the incidence of AKI in two Italian university hospitals from … Read more

Hypoxemia Rare in Early Trauma Care

TOPLINE: Only 5% of patients with trauma experienced significant hypoxemia within the first 8 hours of care, with no difference observed between restrictive and liberal oxygen strategies. METHODOLOGY: This substudy of the randomized TRAUMOX2 trial included 60 adults with trauma injury (median age, 49 years; 75% men) who were randomly assigned to receive either a … Read more

Metabolic Syndrome in Midlife Tied to Early-Onset Dementia

TOPLINE: Metabolic syndrome was associated with a 24% increased risk for young-onset dementia, defined as dementia before the age of 65 years, with stronger associations found in women vs men, younger vs older adults, and individuals with vs without depression, a new study showed. METHODOLOGY: This nationwide population-based cohort study included data from more than … Read more

Donating & Wellbeing: Dexeus University Hospital

The Lifesaving Power of Blood Donation: A Community Effort Blood donation represents a profoundly generous contribution, directly impacting healthcare systems and offering a lifeline to individuals in need globally. It’s a simple act with far-reaching consequences, ensuring hospitals can meet the demands of emergencies, surgeries, and ongoing treatments for conditions like anemia, cancer, and blood … Read more