Study uncovers how tuberculosis bacteria fuel themselves during infection

Researchers at The Hospital for Sick Children (SickKids) have uncovered how the bacteria that causes tuberculosis fuels itself during infection, providing new insights into one of the world’s deadliest infectious diseases.  The study, published in The EMBO Journal, provides the first detailed 3D structure of a protein called EtfD, which the bacterium Mycobacterium tuberculosis uses to extract energy from lipids (fats), along with the first laboratory … Read more

EVA1A regulates fatty acid transporter CD36 in fatty liver disease

Metabolic Dysfunction-Associated Steatotic Liver Disease(MASLD) is characterized by excessive accumulation of lipids in hepatocytes and is closely associated with the rapid rise in insulin resistance, obesity, and diabetes prevalence, making it one of the most common chronic liver diseases worldwide. Fatty liver can lead to systemic metabolic dysfunction and further progress to steatohepatitis, hepatic fibrosis, … Read more

Microbial taxa more likely to be found in people with dyslipidemia

Before the onset of cardiovascular disease symptoms, people often develop dyslipidemia, or abnormal levels of lipids in the blood. Recent studies suggest that microbes in the gut play an important role in how the body produces, regulates and degrades lipids, but the connection isn’t clear.  This week in Microbiology Spectrum, microbiologists in Seoul advance scientists’ … Read more

Colorful japonica rice varieties show unique health-promoting lipids

Rice feeds more than half of the world’s population, yet we still only partly understand the nutrients it contains. More than 85% of the rice we eat is composed of starch, though it also contains some protein (around 10%), small amounts of fat (roughly 2%), a few vitamins, and trace elements. Because fats, or lipids, … Read more

Tuberculosis bacteria stiffen cell membranes to evade immune destruction

Scientists have uncovered an elegant biophysical trick that tuberculosis-causing bacteria use to survive inside human cells, a discovery that could lead to new strategies for fighting one of the world’s deadliest infectious diseases. Tuberculosis kills more than a million people each year and remains a major public health crisis, particularly in Asia, Africa and Latin … Read more

Diabetic nephropathy shows severe biochemical abnormalities

Background and objectives Chronic diabetes mellitus is marked by hyperglycemia and metabolic dysfunction, increasing the risk of complications such as nephropathy. This study aimed to evaluate key biochemical parameters among participants with diabetic nephropathy (DNp), diabetes control (DC), nephropathy control (NC), and healthy control groups. Methods A prospective case-control study was conducted with 200 participants … Read more

Unprocessed beef does not worsen metabolic health in prediabetes

A controlled crossover trial finds that short-term consumption of unprocessed beef is on par with poultry for glucose control, β-cell function, and cardiometabolic markers in people with prediabetes. Study: Effects of Diets Containing Beef Compared with Poultry on Pancreatic β-Cell Function and Other Cardiometabolic Health Indicators in Males and Females with Prediabetes: A Randomized, Crossover … Read more

Researchers discover how Mycoplasma pneumoniae acquires cholesterol from human hosts

A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae-responsible for atypical pneumonia and other respiratory infections-to obtain cholesterol and other essential lipids directly from the human body. The discovery, published in Nature Communications, was co-led by Dr. Noemí Rotllan, from the Sant Pau Research Institute (IR Sant Pau) and … Read more

Adapting Diet to Chronotype Boosts Weight Loss, Gut Health

Among patients with overweight/obesity, a diet adapted to an individual’s chronotype was more effective in promoting weight loss and improving cardiometabolic health and gut microbiota (GM) than a conventional low-calorie diet. “Emerging evidence suggests that aligning dietary patterns with an individual’s circadian rhythm, or chronotype, may optimize metabolic processes and gut microbiota (GM) composition and … Read more

Free Obesity Counseling | Patient Benefits

Nutrition Counseling: Insurance Coverage and Patient Benefits The post Free Obesity Counseling | Patient Benefits appeared first on News Directory 3. Source link