TOPLINE: Administration of dexmedetomidine in patients undergoing cardiac surgery reduced the incidence of postoperative delirium by 38% but was associated with an increased risk for hypotension. METHODOLOGY: Researchers conducted a systematic review and meta-analysis of 18 randomized controlled trials involving 3904 patients undergoing any type of cardiac surgery. They compared the use of dexmedetomidine with … Read more
SAN FRANCISCO — Frailty is hard to define and hard to distinguish from the effects of illness, injury, and medical interventions, but the frailty of patients in the intensive care unit (ICU) can have profound effects on outcomes, including the risk for mortality. In a scientific symposium on frailty in the ICU, presented during the … Read more
Blood oxygen measurements taken with pulse oximeters in hospitals tend to be lower than they really are, according to the Equiox study, which was designed to assess the technology’s measurement capabilities in people with various skin tones. “In a real-world study of critically-ill patients, the performance [of pulse oximeters] was worse than regulatory guidance standards,” … Read more
TOPLINE: Compared with sevoflurane, a combination of remimazolam and flumazenil significantly reduces extubation time and use of ephedrine, while maintaining similar hemodynamic stability, in patients undergoing transcatheter aortic valve implantation (TAVI). METHODOLOGY: Researchers in Japan conducted a prospective, open-label, single-center clinical trial between June 2022 and August 2023 to compare emergence times with sevoflurane or … Read more
Grasselli G, Greco M, Zanella A, Albano G, Antonelli M, Bellani G, Bonanomi E, Cabrini L, Carlesso E, Castelli G, et al. Risk factors associated with mortality among patients with COVID-19 in intensive care units in Lombardy, Italy. JAMA Intern Med. 2020;180(10):1345–55. Article CAS PubMed Google Scholar Nasoufidou A, Kavelidou M, Griva T, Melikidou E, … Read more