Alzheimer’s disease affects an estimated 7.2 million Americans age 65 and older, according to the Alzheimer’s Association. Current tests often measure the levels of two proteins-amyloid beta (Aβ) and phosphorylated tau (p-tau)-in the blood or spinal fluid, but these markers may not fully capture earlier biological changes linked to disease progression. Now, scientists at Scripps … Read more
Jin K, Yao Z, van Velthoven CTJ, Kaplan ES, Glattfelder K, Barlow ST, Boyer G, Carey D, Casper T, Chakka AB, et al: Brain-wide cell-type-specific transcriptomic signatures of healthy ageing in mice. Nature. 2025 (https://doi.org/10.1038/s41586-024-08350-8. Online ahead of print). Liddelow SA, Olsen ML, Sofroniew MV. Reactive Astrocytes and Emerging Roles in Central Nervous System (CNS) … Read more
A groundbreaking study reveals how blood proteins can predict disease risk, track health status, and offer new strategies to combat aging-related conditions. Study: Longitudinal serum proteome mapping reveals biomarkers for healthy ageing and related cardiometabolic diseases. Image Credit: ArtemisDiana / Shutterstock A recent study published in the journal Nature Metabolism identified biomarkers of healthy aging and cardiometabolic … Read more