An ‘AI scientist’, working in collaboration with human scientists, has found that combinations of cheap and safe drugs – used to treat conditions such as high cholesterol and alcohol dependence – could also be effective at treating cancer, a promising new approach to drug discovery. The research team, led by the University of Cambridge, used … Read more
TOPLINE: Pentoxifylline, an anti–tumor necrosis factor alpha agent, did not improve survival outcomes in patients with severe alcohol-associated hepatitis complicated by acute kidney injury (AKI). METHODOLOGY: Severe alcohol-associated hepatitis is a life-threatening condition with corticosteroid treatment as the only therapy demonstrating short-term benefits, leading to the investigation of potential alternative therapies, such as pentoxifylline, particularly … Read more
The most common pathology affecting the pancreas is excess intra-pancreatic fat deposition (IPFD), often called fatty pancreas disease (FPD) — a disorder experienced by roughly one fifth of the world’s population. Although it is more common than type 2 diabetes, pancreatitis, and pancreatic cancer combined, it has remained relatively obscure. By contrast, fatty liver — … Read more
Compared with adults without disabilities, those with disabilities have higher rates of general drug misuse, but information on their misuse of prescription drugs specifically has been lacking. Now, a new analysis has reported that, overall, adults with disabilities are nearly twice as likely to misuse prescription drugs as those without disabilities. Reporting in the American … Read more