Achrol, A. S. et al. Brain metastases. Nat. Rev. Dis. Primer. 5, 5 (2019). Google Scholar Fink, K. & Fink, J. Imaging of brain metastases. Surg. Neurol. Int. 4, 209 (2013). Google Scholar Patchell, R. A. The management of brain metastases. Cancer Treat. Rev. 29, 533–540 (2003). Google Scholar Cho, S. J. et al. Brain … Read more
TOPLINE: In patients with ERBB2-positive metastatic breast cancer (ERBB2+ MBC) and brain metastasis, more than half of deaths were due to central nervous system (CNS)–related causes; however, patients with CNS-only metastasis have significantly longer overall survival than those with both CNS and extracranial metastasis. METHODOLOGY: About one third of patients with ERBB2+ MBC develop brain … Read more
Patients with human epidermal growth factor receptor 2-positive (HER2+) metastatic breast cancer (MBC) with central nervous system (CNS) disease had longer overall survival (OS) and decreased mortality risk compared with those who have extracranial metastasis, according to study results published in JAMA Network Open. The findings suggest that aggressive local and systemic therapies may be … Read more
The treatment landscape for melanoma saw significant advancements in 2024, as highlighted by Elisa Funck-Brentano, MD, PhD, from Ambroise-Paré Hospital in Paris, France, during her presentation at the 2024 Dermatology Days of Paris conference in Paris. Checkpoint Inhibitors in Neoadjuvant Therapy The standard approach for treating resectable stage III melanoma with locoregional metastases has traditionally … Read more