Deep learning based 3D brain metastasis synthesis with configurable parameters for 3D data augmentation

Achrol, A. S. et al. Brain metastases. Nat. Rev. Dis. Primer. 5, 5 (2019). Google Scholar  Fink, K. & Fink, J. Imaging of brain metastases. Surg. Neurol. Int. 4, 209 (2013). Google Scholar  Patchell, R. A. The management of brain metastases. Cancer Treat. Rev. 29, 533–540 (2003). Google Scholar  Cho, S. J. et al. Brain … Read more

Long-term thrombus-free left atrial appendage occlusion via magnetofluids

Alkhouli, M. et al. Left atrial appendage occlusion: current advances and remaining challenges. JACC Adv. 1, 100136 (2022). Article  PubMed  PubMed Central  Google Scholar  Holmes, D. R. et al. Left atrial appendage occlusion: opportunities and challenges. J. Am. Coll. Cardiol. 63, 291–298 (2014). Article  PubMed  Google Scholar  Smit, J. M. et al. Anatomical characteristics of … Read more

Digital CRISPR-based diagnostics for quantification of Candida auris and resistance mutations

WHO Fungal Priority Pathogens List to Guide Research, Development and Public Health Action (World Health Organization, 2022). Fisher, M. C. et al. Tackling the emerging threat of antifungal resistance to human health. Nat. Rev. Microbiol. 20, 557–571 (2022). Article  PubMed  PubMed Central  CAS  Google Scholar  Antibiotic Resistance Threats in the United States 2019 (CDC, 2019). … Read more

Holograms Take 3D Printing to the Next Level – With Amazing Precision and Speed

The method allows the fabrication of millimeter-scale objects within seconds. Credit: © LAPD EPFL Scientists have utilized holographic projections to achieve unprecedented resolution in a light-based 3D printing technique. Traditional 3D printing builds objects layer by layer, but tomographic volumetric additive manufacturing (TVAM) takes a different approach. It uses laser light to illuminate a rotating … Read more

“Science thrives on teamwork”: Scientist Dr Wong Sok Kuan on collaboration and breakthroughs in osteoarthritis research

What’s next for Wong? “My focus is twofold: deepening our understanding of immune modulation in bone metabolism and collaborating with industry and clinical partners to bring these findings from bench to bedside.” Beyond scientific breakthroughs, Wong hopes to nurture the next generation of researchers. “I want to inspire others to pursue impactful research and contribute … Read more

Groundbreaking Neurotechnology Restores Motor Function in SMA

Neurostimulation of sensory spinal nerves improved movement in SMA patients by restoring neural function, as shown in a small clinical trial. This approach may have broader applications for other neurodegenerative diseases. A new electrical stimulation therapy for spinal muscle atrophy (SMA) has shown promise in reactivating motor neurons and improving movement. In a pilot clinical … Read more