Transfusion Strategies Show No QOL Improvement in Anemia Patients

Micah T. Prochaska, MD, MSc | Image Credit: University of Chicago School of Medicine A recent secondary analysis of data from the Myocardial Ischemia and Transfusion (MINT) trial has found no difference in quality of life (QOL) outcomes between liberal versus restrictive transfusion strategies in patients with myocardial infarction (MI) and anemia.1 Thanks to advances … Read more

Secukinumab Demonstrates Long-Term Safety for Psoriasis and PsA

New findings from a real-world study has demonstrated long-term safety of secukinumab in people with psoriasis (PsO), psoriatic arthritis (PsA), and ankylosing spondylitis (AS).1 “Patients with immune-mediated inflammatory diseases such as PsO, PsA and AS, require prolonged treatment and are more susceptible to developing AEs as observed in clinical studies and case reports. Therefore, there … Read more

Increased prevalence and risk of atherosclerotic cardiovascular disease in individuals with Type 1 diabetes and metabolic dysfunction-associated steatotic liver disease | Cardiovascular Diabetology

Van der Schueren B, Ellis D, Faradji RN, Al-Ozairi E, Rosen J, Mathieu C. Obesity in people living with type 1 diabetes. Lancet Diabetes Endocrinol. 2021;9(11):776–85. PubMed  Google Scholar  Bielka W, Przezak A, Molęda P, Pius-Sadowska E, Machaliński B. Double diabetes-when type 1 diabetes meets type 2 diabetes: definition, pathogenesis and recognition. Cardiovasc Diabetol. 2024;23(1):62. … Read more

Advanced Treatments and Collaborative Care Closer to Home

Nicholas Todhunter, DO Credit: AHN The neuroscience program at AHN Saint Vincent Hospital plays a vital role in providing advanced neurological care to patients in the Erie region — reducing the need to travel to a major city for many conditions. Without this local access, many would face delays in receiving life-saving or quality-of-life-enhancing treatment. … Read more

Lower Blood Pressure May Offer Benefits Even for the Very Elderly

Adults aged 80 and older experience the highest prevalence of cardiovascular disease, yet the optimal blood pressure targets for this group have been unclear in clinical guidelines. Now, a new study from Yale School of Medicine (YSM) suggests that intensive blood pressure management may offer important benefits for very elderly patients. As the American population … Read more

Arthritis Precedes Psoriasis More Often Than Expected

Hannah Y. Gantz Credit: Linkedin New research has found that symptoms of psoriatic arthritis (PsA) often precede psoriasis (PsO) development and psoriasis skin lesions.1 “PsA occurs in about 30% of patients with PsO, and an additional 5%–15% of psoriasis patients may have undiagnosed PsA. The current dogma is that PsO skin lesions generally occur before … Read more

LAP May Predict Risk of Hyperuricemia and Gout

Lipid accumulation product had high potential in predicting the risk of gout/hyperuricemia in new research, offering a potentially modifiable risk factor for preventing gout.1 “Traditional metrics for evaluating obesity, such as Body Mass Index (BMI) and Waist Circumference (WC), have been widely utilized; however, they exhibit significant limitations in accurately reflecting the complex nature of … Read more

Unlocking New Insights into Cardiovascular Risk with Accurate Lp(a) Measurement

Despite decades of progress in identifying cardiovascular risk factors and prevention efforts, cardiovascular disease (CVD) remains the leading cause of death worldwide.1 A growing body of evidence has underscored the role of Lipoprotein(a) [Lp(a)] in CVD risk. In addition to its independent contribution to atherosclerosis, thrombosis, and aortic valve calcification, high Lp(a) levels can also … Read more

Impact of sodium–glucose transport protein-2 (SGLT2) inhibitors on the inflammasome pathway in acute myocardial infarction in type 2 diabetes mellitus: a comprehensive review | Cardiovascular Diabetology

Yang L, Zhang X, Wang Q. Effects and mechanisms of SGLT2 inhibitors on the NLRP3 inflammasome, with a focus on atherosclerosis. Front Endocrinol (Lausanne). 2022;13:992937. PubMed  Google Scholar  Kim SR, Lee SG, Kim SH, Kim JH, Choi E, Cho W, et al. SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with … Read more

OCT Features May Signal Risk of Retinal Atrophy, Study Suggests

Image Credit: Adobe Stock A recent study from Sapienza University of Rome has indicated that optical coherence tomography (OCT) features such as type 2 macular neovascularization (MNV), reductions in outer nuclear layer (ONL) and central foveal thickness (CFT), and intraretinal fluid (IRF) presence at baseline could signal higher risks of retinal atrophy (RA) in treatment-naïve … Read more