Heavily processed foods may raise heart disease risk beyond poor nutrition alone

A new review links ultra-processed foods and their additives to higher cardiovascular risk, pointing to large human studies and inflammation-related mechanisms that may help explain why heavily processed diets can harm heart health. Key takeaways Higher intake of ultra-processed foods was associated with a higher risk of cardiovascular disease. Food additives may also contribute to … Read more

Digital CBT reduces anxiety and improves recovery after heart attack

Digital CBT treatment reduced cardiac-related anxiety and improved patients’ quality of life and physical function after a heart attack. This is shown in a new randomised study published in Journal of the American College of Cardiology, in which researchers at Karolinska Institutet compared digital CBT with standard care. Many people who suffer a heart attack … Read more

Small, combined improvements to sleep, diet and physical activity may yield major heart benefits

New research shows that small improvements to sleep, diet quality, and physical activity, made in combination, are associated with a significantly reduced risk of major cardiovascular events such as stroke, heart attacks, and heart failure. The study followed more than 53,000 adults from UK Biobank over an eight‑year period and found that making even modest improvements … Read more

Blood pressure readings may help identify future dementia risk

Measures of blood vessel health derived from routine blood pressure readings may help identify adults at increased risk for dementia, according to research being presented at the American College of Cardiology’s Annual Scientific Session (ACC.26). The findings from two studies that tracked patterns of arterial stiffness over time align with growing evidence that uncontrolled hypertension … Read more

Clinicians show modest response to elevated lipoprotein levels in low-risk patients

Elevated Lipoprotein(a) [Lp(a)] is an independent, genetically determined risk factor for atherosclerotic cardiovascular disease (ASCVD), with levels >50 mg/dL affecting 20–30% of the global population. Despite therapeutic limitations, interest in Lp(a) has increased, driven by its prognostic value and the emergence of targeted therapies. However, with increasing guideline-directed Lp(a) testing, clinician response to elevated concentrations, … Read more

New review calls for biologically grounded approach to psychiatric diagnosis

A comprehensive invited review published today in Brain Medicine confronts one of the most persistent paradoxes in modern medicine: psychiatry remains the only major clinical discipline that diagnoses complex illness primarily through conversation and symptom checklists, while fields such as oncology and cardiology long ago embraced laboratory markers, imaging, and molecular profiling. The review, authored … Read more

Allergy-associated acute coronary syndrome without anaphylaxis in a prospective observational study

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Efficient cardiac MRI multi-structure segmentation for cardiovascular assessment with limited annotation by integrating data-level and network-level consistency

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Specific gut microbes are associated with the incidence of cardiometabolic disease in the HELIUS cohort

Witkowski, M., Weeks, T. L. & Hazen, S. L. Gut microbiota and cardiovascular disease. Circ. Res. 127, 553–570 (2020). Google Scholar  Kootte, R. S. et al. Improvement of insulin sensitivity after lean donor feces in metabolic syndrome is driven by baseline intestinal microbiota composition. Cell Metab. 26, 611–619.e6 (2017). Google Scholar  Verhaar, B. J. H. … Read more

A latent class analysis of cardiometabolic risk factors and the predicted prevalence of subclinical atherosclerosis in middle-aged Swedish adults

Jebari-Benslaiman, S. et al. Pathophysiology of Atherosclerosis. Int. J. Mol. Sci. 23 https://doi.org/10.3390/ijms23063346 (2022). Bergstrom, G. et al. Prevalence of subclinical coronary Artery atherosclerosis in the general population. Circulation 144, 916–929. https://doi.org/10.1161/CIRCULATIONAHA.121.055340 (2021). Google Scholar  Lind, L. et al. Obesity is associated with coronary artery stenosis independently of metabolic risk factors: The population-based SCAPIS study. … Read more