TOPLINE: Neonates born preterm with very low birth weight (VLBW) exposed to multiple perinatal antibiotics were at an increased risk for impaired lung function and asthma episodes at early school age, according to a new study. METHODOLOGY: This population-based, multicentre cohort analysis included 3820 neonates born preterm with VLBW (< 1500 g; median gestational age, … Read more
Editor’s Note:The Case Challenge series includes difficult-to-diagnose conditions, some of which are not frequently encountered by most clinicians, but are nonetheless important to accurately recognize. Test your diagnostic and treatment skills using the following patient scenario and corresponding questions. If you have a case that you would like to suggest for a future Case Challenge, … Read more
The teratogenic risk of antiepileptic drugs (AEDs) has been a major concern in pharmacovigilance over the past several decades. However, neurodevelopmental and autism-related risks associated with these medications have gradually emerged. Although international registries provide information, they are not sufficiently comprehensive to fully assess the risks posed by many AEDs introduced in the past 20 … Read more
TOPLINE: Nearly 19 million US children live with at least one parent meeting Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition; DSM-5) criteria for substance use disorder (SUD), representing one quarter of all US children in 2023. Over 6.1 million of these children have parents with comorbid SUD and mental illness, making them particularly … Read more
Children of immigrants from India were more likely to develop atopic diseases if born in the United States or Canada than those who emigrated with their parents, according to new research published in The Journal of Allergy and Clinical Immunology: Global. Additionally, parents overall had lower rates of conditions like asthma and food allergies than … Read more
Emergencies happen anywhere, anytime, and sometimes medical professionals find themselves in situations where they are the only ones who can help. Is There a Doctor in the House? is a Medscape series telling these stories. “Dad, they just called for a doctor.” It was a routine flight home to Hawaii from Salt Lake City with my … Read more
Key Takeaways An 11-year-old boy presented with a 4-month history of swelling in the left knee joint. He had a knee injury 4 months earlier, which had required a puncture. The wound was crusted and healed. Diagnosis was confirmed by joint incision and histopathologic examination of the joint fluid. The case reported by orthopaedic surgeon … Read more
Medically supervised resistance training and adequate protein intake may help minimize the loss of lean body mass in people taking glucagon-like peptide 1 receptor agonists (GLP-1 RAs) for weight loss, new data suggest. The findings came from a prospective 6-month study of 200 adults with overweight or obesity who received education on resistance training and … Read more
Cardiology 2025, the 28th Annual Update on Pediatric and Congenital Cardiovascular Disease, took place from February 19 to 23 in Lake Buena Vista, Florida. The conference, hosted by the Children’s Hospital of Philadelphia, brought together a diverse community of pediatric and congenital cardiovascular professionals and advocates, all united by this year’s theme: Hope, Heal, and … Read more
A new systematic review and network meta-analysis showed few differences in the cardiovascular (CV) effects of stimulants and noradrenaline reuptake inhibitors used to treat attention-deficit/hyperactivity disorder (ADHD). Short-term use of amphetamines, atomoxetine, lisdexamfetamine, methylphenidate, and viloxazine was associated with small increases in blood pressure (BP), pulse, or both in children, adolescents, and adults. Further, the … Read more