Math-based model helps optimize treatment for chronic eczema

Anyone with a chronic illness understands the struggle of living with a disease that is deeply unpredictable. Many such illnesses are characterized by long periods of remission broken up by sudden, debilitating flare-ups. Sometimes these flare-ups have obvious causes, but often they seem to come out of nowhere, which can be frustrating and unpleasant. The … Read more

How Household Fuels Are Worsening Eczema and Asthma in South African Children

In many households in Mabopane and Soshanguve — townships on the northern outskirts of South Africa’s City of Tshwane that are marked by high poverty, unemployment and informal economic activity — evenings follow a familiar pattern. When electricity cuts occur or power becomes unaffordable, families turn to gas stoves, paraffin heaters, or wood and coal … Read more

Chronic eczema burdens physical and mental health in older people

Eczema is a group of inflammatory and chronic skin conditions, and it is the most common skin disease among older people. As many as one in two people aged over 60 suffer from some form of eczema. A large population-based study conducted at the University of Oulu shows that the condition can have a significant … Read more

First topical CRISPR gene therapy corrects disease-causing mutations in human skin

Gene-editing tools like CRISPR have unlocked new treatments for previously uncurable diseases. Now, researchers at the University of British Columbia are extending those possibilities to the skin for the first time. The UBC team, together with researchers from the Berlin Institute of Health at Charité in Germany, has developed the first gene therapy capable of … Read more

Household environments may affect the likelihood of children developing eczema

Household environments, including owning a dog, may affect the likelihood of children developing eczema, according to an analysis of almost 300,000 people from across Europe. The prevalence of eczema has rapidly risen in industrialised areas over the past 30 years, now affecting approximately 20% of children and 10% of adults in high-income countries. The new … Read more

Early contact with pet dogs protects genetically susceptible children from eczema

Having a dog at home could help to prevent eczema in children who are genetically prone to the condition, a study suggests. Children with a change in their DNA that increases their chance of developing eczema were less likely to have the condition if they were exposed to a dog in early life, researchers say. … Read more

Atopy Rises in Indian Immigrant Kids, Study Finds

Children of immigrants from India were more likely to develop atopic diseases if born in the United States or Canada than those who emigrated with their parents, according to new research published in The Journal of Allergy and Clinical Immunology: Global. Additionally, parents overall had lower rates of conditions like asthma and food allergies than … Read more

Rising Atopic Dermatitis in Older US Adults

Archyde Atopic Dermatitis Cases surge among Elderly Americans, Study Reveals Gender Disparities WASHINGTON — New research indicates a significant rise in atopic dermatitis, commonly known as eczema, among the oldest adults in the United States. The study, analyzing data from 1990 to 2019, reveals an 85.53% increase in cases among those aged 80 and older, … Read more

How your skin’s microbes shape immunity, inflammation, and chronic skin disease

From babyhood to adulthood, the bacteria and fungi on your skin help train your immune system—but when that balance tips, chronic inflammation can follow. This new review reveals how and why. Study: Conversation between skin microbiota and the host: from early life to adulthood. Image Credit: Corona Borealis Studio / Shutterstock In a recent review published in … Read more

Organophosphate Pesticide Exposure Linked to Atopic Dermatitis Risk

New findings suggest that exposure to organophosphate pesticides (OPPs), especially dimethylphosphate, may be linked to an increase in atopic dermatitis risk among adults.1 These conclusions resulted from a recent analysis authored in part by YueHua Men, from the Peking University Third Hospital Department of Dermatology in Beijing. Men and colleagues noted that such pesticides are … Read more