Many Definitions, No Easy Solutions

SAN FRANCISCO — Frailty is hard to define and hard to distinguish from the effects of illness, injury, and medical interventions, but the frailty of patients in the intensive care unit (ICU) can have profound effects on outcomes, including the risk for mortality. In a scientific symposium on frailty in the ICU, presented during the … Read more

Fracture Risk Lower With Semaglutide vs Sleeve

Orlando, Fla. — Fracture risk in people treated for obesity appears significantly lower with semaglutide (Wegovy) vs sleeve gastrectomy, new data suggest. Previous animal studies have suggested a dose-dependent effect of glucagon like peptide 1 (GLP-1) receptor agonists on trabecular bone, including increased osteoblast activity, reduced apoptosis, and suppressed osteoclast activity. However, human data have … Read more

Anaphylaxis Severity Rises With Age in Emergency Care

TOPLINE: Older adults who present to the emergency department (ED) with anaphylaxis may be more likely than younger adults to be hospitalized and to have medications or intravenous contrast as triggers, a study showed. Older patients also may be less likely to receive epinephrine from emergency medical services (EMS). METHODOLOGY: Researchers examined data from ED … Read more

Early Postpartum IUD Doesn’t Spike Healthcare Utilization

TOPLINE: Healthcare utilization after immediate and delayed intrauterine device (IUD) placement postpartum was comparable, with the immediate placement group making slightly fewer visits to obstetricians or gynecologists (OB/GYNs). While immediate placement was associated with increased rates of imaging, it showed lower rates of laparoscopic surgery for IUD-related complications. METHODOLOGY: Researchers conducted a retrospective cohort study … Read more