The Child and Youth Maltreatment Section of the Canadian Paediatric Society (CPS) has released a new Practice Point for the assessment of children with suspected traumatic head injury related to child maltreatment (THI-CM). This type of injury “is not rare and frequently results in significant morbidity for the child and family,” the CPS told Medscape … Read more
Orlando, Fla. — Fracture risk in people treated for obesity appears significantly lower with semaglutide (Wegovy) vs sleeve gastrectomy, new data suggest. Previous animal studies have suggested a dose-dependent effect of glucagon like peptide 1 (GLP-1) receptor agonists on trabecular bone, including increased osteoblast activity, reduced apoptosis, and suppressed osteoclast activity. However, human data have … Read more
TOPLINE: A substantial proportion of perimenopausal and menopausal women expressed willingness to undergo assessment for osteoporosis, especially among those of Chinese ethnicity and those with an older age, fracture history, and higher scores in perception of their osteoporosis risk. METHODOLOGY: Researchers conducted this cross-sectional study utilizing self-administered questionnaires to determine the factors that affect the … Read more
TOPLINE: Compared with a conventional ad libitum Mediterranean diet, an energy-restricted Mediterranean diet along with physical activity helped preserve bone mineral density (BMD) during weight loss in older women with metabolic syndrome, showing the most benefits at the lumbar level over a 3-year period. METHODOLOGY: Individuals with obesity and older adults exhibit increased vulnerability to … Read more
The popularity of glucagon-like peptide 1 (GLP-1) receptor agonists has led to a concomitant increase in the need to understand the potential perioperative ramifications of taking these drugs, from increased aspiration risk to prosthetic joint infections. At the American Academy of Orthopaedic Surgeons 2025 Annual Meeting, researchers presented an array of studies looking at the … Read more
Archyde Methotrexate and Fracture risk: A Critical Re-evaluation for U.S. Patients Table of Contents 1. Methotrexate and Fracture risk: A Critical Re-evaluation for U.S. Patients 2. The Core Issue: Methotrexate-Related Osteopathy (MTXO) 3. The Study: A Closer look at Fracture Risk 4. Why This Matters to U.S.Patients 5. Addressing potential Counterarguments 6. Fresh Insights and … Read more
TOPLINE: In patients with methotrexate osteopathy (MTXO) insufficiency fractures, continuing MTX led to a significantly higher risk for subsequent fractures, with nearly all patients who continued MTX experiencing either further insufficiency fractures or major osteoporotic fractures. METHODOLOGY: Researchers conducted a retrospective case note review to assess whether the continuation of MTX after MTX-associated insufficiency fractures, … Read more
Women in early menopause treated with zoledronate in just two infusions, 5 years apart, show a significantly reduced risk of sustaining a vertebral fracture and better maintenance of bone mineral density (BMD) over a 10-year period than those receiving just one or no infusions over the period, suggesting the infrequent, early dosing to be a … Read more