How to Freeze and Thaw Brain Tissue

Stories about humans waking up from cryosleep have dominated popular culture for decades in the Alien films, Cameron’s Avatar, and Nolan’s Interstellar. While these films are out there, space- and time-wise, we know the science exists offscreen. Globally, there are about 500 people in cryogenic preservation: 300 of them in the United States. Thousands more … Read more

How to Freeze and Thaw Brain Tissue

Stories about humans waking up from cryosleep have dominated popular culture for decades in the Alien films, Cameron’s Avatar, and Nolan’s Interstellar. While these films are out there, space- and time-wise, we know the science exists offscreen. Globally, there are about 500 people in cryogenic preservation: 300 of them in the United States. Thousands more … Read more

AI in Ulcerative Colitis: Enhancing Clinical Workflow

Ryan W. Stidham, MD, MS Artificial intelligence (AI) is used in ulcerative colitis to assist in the assessment, monitoring, and management of disease. To explain how this technology is being applied in the clinical setting, Janelle McSwiggin, MSN, RN, spoke with Ryan W. Stidham, MD, MS, associate professor in the Division of Gastroenterology at University … Read more

5 Risk Factors at 50 Can Steal a Decade of Life

Five classic risk factors for cardiovascular disease — high blood pressure, high cholesterol, obesity, diabetes, and smoking — at age 50 can reduce life expectancy by more than 10 years. This is the conclusion of an international study led by German researchers and presented at the 2025 American College of Cardiology Scientific Session. “These five … Read more

Computer-Aided Colonoscopy Not Ready for Prime Time

An American Gastroenterological Association (AGA) multidisciplinary panel has reached the conclusion that no recommendation can be made for or against the use of computer-aided detection (CADe)–assisted colonoscopy for colorectal cancer (CRC), the third most common cause of cancer mortality in the United States. The systematic data review is a collaboration between the AGA and The … Read more

Carbohydrate Intolerance Common in Gut-Brain Disorders

TOPLINE: A substantial proportion of patients with disorders of gut-brain interaction had carbohydrate intolerance. These patients experienced more severe irritable bowel syndrome (IBS) and somatic symptoms, along with a lower quality of life, than those without carbohydrate intolerance. METHODOLOGY: Patients with disorders of gut-brain interaction may have symptoms of carbohydrate maldigestion or malabsorption; however, routine … Read more

Blood Test Predicts Melanoma Recurrence

TOPLINE: Droplet digital polymerase chain reaction (PCR) measurements of circulating tumor DNA (ctDNA) identify patients with stage III melanoma who are at high risk for early recurrence during adjuvant targeted therapy. The blood-based biomarker outperforms traditional prognostic indicators including tumor mutational burden and interferon gamma gene expression. METHODOLOGY: Cell-free ctDNA is an established measure of … Read more

Resistance Training + Protein May Lower GLP-1 RA Muscle Loss

Medically supervised resistance training and adequate protein intake may help minimize the loss of lean body mass in people taking glucagon-like peptide 1 receptor agonists (GLP-1 RAs) for weight loss, new data suggest. The findings came from a prospective 6-month study of 200 adults with overweight or obesity who received education on resistance training and … Read more

Pediatric Cardiology: Highlights From Cardiology 2025

Cardiology 2025, the 28th Annual Update on Pediatric and Congenital Cardiovascular Disease, took place from February 19 to 23 in Lake Buena Vista, Florida. The conference, hosted by the Children’s Hospital of Philadelphia, brought together a diverse community of pediatric and congenital cardiovascular professionals and advocates, all united by this year’s theme: Hope, Heal, and … Read more

Risk Patterns Guide Surveillance Colonoscopy Decisions

TOPLINE: A new study revealed that patients with high-risk findings at both baseline and first surveillance colonoscopy (SC1) had a significantly higher risk for colorectal cancer (CRC) than the general population, requiring a second surveillance visit. Conversely, those with low-risk findings at SC1 did not require a second surveillance visit, regardless of their baseline findings. … Read more