Sero-prevalence of hepatitis B virus and associated risk factors among pregnant women attending Demartino hospital, Mogadishu, Somalia | BMC Infectious Diseases

Study design, period, and setting An institution-based cross-sectional study was conducted between January and February 2024 to determine the seroprevalence of HBsAg and its associated factors among pregnant women attending Demartino Hospital in Mogadishu, Somalia. The cross-sectional design was chosen because it is appropriate for estimating disease prevalence at a single point in time, aligning … Read more

The characteristics of peripheral blood lymphocyte main subsets in rheumatoid arthritis patients concurrent with hepatitis b virus infection: a retrospective cohort study | BMC Infectious Diseases

Study population Patients (n = 298) who fulfilled the 1987 revised criteria of the American College of Rheumatology (ACR) or the 2010 ACR/European League Against Rheumatism criteria for RA classification were retrospectively recruited from the Zhejiang University School of Medicine-Affiliated Jinhua Hospital between March 2022 and March 2023. Patients with RA (n = 43) who had hepatitis … Read more

Are we prepared for the next outbreak?

With over 600 known human viruses and new ones emerging, experts highlight how climate change, globalization, and zoonotic spillover are accelerating viral threats—are we ready for the next pandemic? Invited Review: Human viruses: An ever-increasing list. Image Credit: Lightspring / Shutterstock In a recent review published in the journal Virology, researchers examined the increasing diversity of human … Read more

New guidelines for hepatitis B virus reactivation management

New recommendations address advances in immunosuppressive therapies and highlight antiviral prophylaxis for high-risk patients. Study: AGA Clinical Practice Guideline on the Prevention and Treatment of Hepatitis B Virus Reactivation in At-Risk Individuals. Image Credit: Josep Suria / Shutterstock.com In a recent study published in Gastroenterology, researchers update clinical practice guidelines for how to prevent and monitor … Read more

Alcohol consumption increases risks of cirrhosis and HCC in patients with HBV infection

Background and aims The quantitative effects of alcohol consumption on cirrhosis and hepatocellular carcinoma (HCC) in hepatitis B virus (HBV) infection are unknown. This study aimed to establish a dose-dependent model of alcohol consumption on the risks of cirrhosis and HCC. Methods PubMed, Embase, the Cochrane Library, Web of Science, and four Chinese databases were … Read more

Evaluation of the role of unconventional prefoldin RPB5 interactor (URI1) in hepatitis B virus infection | Virology Journal

Schlaak JF. Current Therapy of Chronic Viral Hepatitis B, C and D. J Pers Med. 2023;13:964. Article  PubMed  PubMed Central  Google Scholar  Burén S, Gomes AL, Teijeiro A, Fawal M-A, Yilmaz M, Tummala KS, et al. Regulation of OGT by URI in Response to Glucose Confers c-MYC-Dependent Survival Mechanisms. Cancer Cell. 2016;30:290–307. Article  CAS  PubMed  … Read more