polycystic ovarian disease

Continuing Metformin Reduces PCOS Pregnancy Risks

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TOPLINE: Continuing metformin throughout the first trimester in women with polycystic ovary syndrome (PCOS) showed the potential to reduce miscarriage risk (odds ratio [OR], 0.64) and increase clinical pregnancy rates (OR, 1.57) compared with placebo. A meta-analysis of 12 randomized controlled trials involving 1708 women suggested that stopping metformin at pregnancy confirmation might be less … Read more

Don’t Overlook First-Gen Anti-Obesity Medications

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With the explosive popularity of glucagon-like peptide 1 (GLP-1) agonists, physicians say a key avenue in treating obesity is being underutilized by many clinicians: First-generation anti-obesity medications (AOMs). “First-generation medications don’t get as much attention as the newer ones,” said Courtney Younglove, MD, an obesity specialist and founder of Heartland Weight Loss in Overland Park, … Read more