prostatic

Can Adding Radium-223 to RT Boost Prostate Cancer Outcomes?

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TOPLINE: Adding radium-223 dichloride (Ra223) to metastasis-directed stereotactic ablative radiotherapy (SABR) did not improve progression-free survival compared with SABR alone in men with bone-only oligometastatic castration-sensitive prostate cancer, according to a phase 2 trial. However, the authors identified two potential prognostic biomarkers — high-risk DNA mutations and T-cell receptor repertoire diversity — to predict progression-free … Read more

‘I Forgot I Was 7000 Miles Away’ During Surgical First

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On a cold Wednesday morning in January, Ruben Olivares, MD, sat down at a computer workstation in Cleveland to perform surgery on a man with prostate cancer. Olivares, a urologist at Cleveland Clinic, Cleveland, directed a robot to send high-intensity, focused ultrasound waves to the tumor. But this time, the patient was not in a … Read more

Improved Treatment for Low-Grade PC Lesions

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Archyde Expert Groups Advocate for Refined Approach to Diagnosing Indolent prostate Cancer May 8, 2025 Two leading international pathology societies are urging a shift in how indolent prostate cancers are detected and diagnosed, aiming to reduce overtreatment and improve patient outcomes. Teh Genitourinary Pathology Society (GUPS) and the International Society of Urological Pathology (ISUP) recently … Read more

Radiotherapy for Prostate Cancer: What Approach Works Best?

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TOPLINE: Moderately hypofractionated radiotherapy, both isodose and dose-escalated, led to progression-free survival outcomes similar to that achieved with conventionally fractionated radiotherapy in patients with prostate cancer, but the dose-escalated regimen came with an increased risk for toxicities compared with the conventional approach, according to findings from a recent meta-analysis. METHODOLOGY: Moderately hypofractionated radiotherapy is now … Read more

EMA Launches Review of Finasteride for Suicidal Ideation

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The Pharmacovigilance Risk Assessment Committee of the European Medicines Agency (EMA) has started a review of medicines containing finasteride and dutasteride following concerns about associated suicidal ideation and behaviors.  Medicines containing finasteride (5 mg tablets) and dutasteride (0.5 mg capsules) are approved to treat symptoms of benign prostatic hyperplasia. Products containing finasteride are also used … Read more

‘Man Van’ Diagnoses Nonmetastatic Prostate Cancers

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Among more than 3000 men from low-income communities who were screened for various health issues at mobile clinics, one had stage IV and none had metastatic prostate cancer. These were among the findings of a study presented by lead author Masood Moghul, MBBS, at the 2025 American Society of Clinical Oncology (ASCO) Genitourinary Cancers Symposium … Read more