Groundbreaking research reveals how gut microbes and dietary soy can influence the outcome of cancer treatments, paving the way for a new frontier in personalized oncology.
Study: Microbiome metabolism of dietary phytochemicals controls the anticancer activity of PI3K inhibitors. Image Credit: CI Photos / Shutterstock
In a recent study published in the journal Cell, researchers demonstrated that phytochemicals and their microbiome-derived compounds regulate the anticancer activity of phosphatidylinositol 3-kinase (PI3K) inhibitors (PI3Ki).
The findings challenge previous assumptions by demonstrating that the effectiveness of these drugs is not primarily governed by dietary carbohydrate content, but by the presence or absence of certain plant-derived compounds and their microbial…