Often diagnosed when surgery is no longer an option, pancreatic cancer is one of the most difficult cancers to treat and has one of the lowest rates of survival among major malignancies. Like many solid tumors, the most common type of pancreatic cancer, pancreatic ductal adenocarcinoma (PDAC), is shielded by the desmoplastic matrix-a dense barrier … Read more
From blood sugar control to immune and gut effects, camel milk is drawing scientific interest as a functional food, but this review says any promise must be weighed against the real safety risks of drinking it raw. Review: Camel Milk as a Functional Food: Nutritional Composition, Health-Promoting Benefits, and Safety Considerations. Image Credit: MehmetO / … Read more
A new preclinical study shows that red blood cells can be tagged in vivo and used as long-lasting carriers for imaging agents and therapies, opening a new route for safer drug delivery and vascular imaging. Study: In vivo metabolic tagging and targeting of circulating red blood cells. Image Credit: The1969 Studio / Shutterstock In a … Read more
Despite hopes raised by earlier observational studies and biomarker shifts, The Lancet trials found that oral semaglutide did not meaningfully slow clinical progression in early Alzheimer’s disease over two years. Key Takeaways Oral semaglutide did not slow cognitive or functional decline in people with early Alzheimer’s disease. Two large phase 3 trials independently reached the … Read more
Iconeus, a French neuroimaging company developing functional ultrasound (fUS) solutions for real-time brain activity imaging, today announced the creation of its U.S. entity, Iconeus Inc. – a key milestone in supporting the adoption of functional ultrasound in preclinical neuroscience research. The new U.S. presence will enable closer collaboration with American academic laboratories, research institutes, pharmaceutical … Read more
A new preclinical study in mice shows that precancerous cells in the pancreas can be eliminated before they have the chance to become tumors. Using an experimental therapy to target microscopic precancerous lesions in the pancreas nearly doubled survival in mouse models of pancreatic ductal adenocarcinoma (PDAC) compared to the same treatment given after cancer … Read more
A topical cream activated the skin’s immune defenses and suppressed tumor growth in two preclinical models of cutaneous squamous cell carcinoma (cSCC), one of the most common cancers in the world, according to a study published today in the Journal of Clinical Investigation. Developed by researchers at the Perelman School of Medicine at the University … Read more
Mayo Clinic researchers have identified a drug-and-supplement combination therapy that is capable of reducing the harmful effects… The post Chronic Kidney Inflammation: New Treatment Strategy appeared first on Archynetys. Source link
Mayo Clinic researchers have identified a drug-and-supplement combination therapy that is capable of reducing the harmful effects of senescent cells – also known as “zombie cells” – in diabetic kidney disease. In eBioMedicine, a publication of The Lancet, the team reported that the combination of the cancer drug dasatanib and a naturally occurring substance known as quercetin decreased inflammation … Read more
A major study of US veterans suggests that GLP-1 diabetes medications may influence addiction-related outcomes, revealing a surprising connection between metabolic treatments and substance use risk. Study: Glucagon-like peptide-1 receptor agonists and risk of substance use disorders among US veterans with type 2 diabetes: cohort study. Image Credit: Kotcha K / Shutterstock A recent study … Read more