Blood-based test could personalize treatment for patients with HPV-associated throat cancer

Researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) are advancing the understanding of a promising blood test that could personalize treatment and surveillance for patients with human papillomavirus (HPV)-associated throat cancer. The research, published in JAMA Otolaryngology – Head … Read more

State-run insurance plans for foster kids leave some of them without doctors

Ollie Super has moved in and out of cancer treatment since she was diagnosed with neuroblastoma as a toddler in foster care. Now 8, the second grader is dealing with it again. Her cancer came back late last year. Ollie’s parents, who adopted her in 2020, tried to sign her up for a clinical trial … Read more

Genomic study advances prioritization of variants in cancer diagnostics

Hiroshima University researchers have developed a practical framework to identify candidate pathogenic variants hidden among the large number of variants of uncertain significance (VUS) detected in comprehensive genomic profiling (CGP) of cancers. This framework could improve the accuracy of precision oncology by more reliable prioritization of VUS. Comprehensive genomic profiling (CGP) enables comprehensive detection of … Read more

New urine test shows which UTI antibiotic works in under six hours

A new direct-from-urine test could help doctors choose the right antibiotic for UTIs on the same day, potentially improving patient outcomes while reducing delays that can fuel resistance and serious complications. Patients with urinary tract infections (UTIs) could receive the right antibiotic far sooner, thanks to a new test that produces results within hours rather … Read more

‘I was diagnosed with incurable brain cancer on holiday’

One minute Joanna James was relaxing on a sun lounger, enjoying a holiday with her partner to celebrate her 50th birthday – and the next, she was unable to speak, being cared for in hospital and diagnosed with incurable brain cancer. After extensive chemotherapy and radiotherapy back home in Yorkshire, there was nothing more the … Read more

Study explores racial differences in gastric cancer immunotherapy outcomes

Advanced gastric cancer remains one of the deadliest malignancies, with a 5-year overall survival rate below 10%. In recent years, combining chemotherapy with PD-1 or PD-L1 inhibitors has become standard first-line care for previously untreated HER2-negative disease. Yet major global trials and subgroup analyses have pointed to a recurring pattern: Asian patients often experience stronger … Read more

iXCells Biotechnologies joins international collaboration to evaluate chemotherapeutic toxicity in human organoids

iXCells Biotechnologies (“iXCells”), a leading provider of human cell-based solutions and custom iPSC services, today announced it has entered an international collaboration with Rosebud Biosciences (“Rosebud”), Kantify, and Incite to evaluate off-target chemotherapeutic toxicities in patient-specific organoids. Building on iXCells’ recent partnership with Rosebud and funded by Incite, the project will initially focus on predicting … Read more

New mechanism driving glioblastoma growth offers potential treatment targets

Australian researchers have uncovered a critical mechanism driving the growth and spread of glioblastoma – one of the most aggressive and lethal forms of brain cancer – potentially paving the way for more effective treatments. In a new study led by Adelaide University scientists from the Centre for Cancer Biology (CCB), researchers identified a previously … Read more

Exercise cuts ‘chemo brain’ and fatigue in cancer patients

A simple home-based exercise plan helped patients stay active during chemotherapy, reducing mental fatigue and showing potential to ease “chemo brain”, especially in those on shorter treatment cycles.  Study: Effects of Exercise on Cognitive Impairment in Patients Receiving Chemotherapy: A Multicenter Phase III Randomized Controlled Trial. Image credit: NDAB Creativity/Shutterstock.com  Cancer-related cognitive impairment occurs in … Read more