Immune scaffold predicts onset weeks early

A retrievable immune scaffold reveals a 5–7 week presymptomatic window for tracking type 1 diabetes progression, long before blood sugar tests turn positive.  Study: Longitudinal monitoring of type 1 diabetes progression to disease onset. Image credit: Halfpoint/Shutterstock.com A recent study published in Science Advances described the application of subcutaneous microporous scaffolds, viz., immunological niches (INs), for … Read more

Study reveals key role of Treg cells in preventing autoimmune responses

During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and viruses from self-antigens that are expressed by cells of the body. If not, the immune system can mistakenly attack its own cells, causing lasting damage to tissue and potential long-term disease. New research from the University of Chicago … Read more

LJI scientists discover a potential new target for treating Parkinson’s disease

Scientists at La Jolla Institute for Immunology (LJI) have found a potential new target for treating Parkinson’s disease. Their new research reveals how a protein in brain cells may drive Parkinson’s onset-and offers a possible explanation for why Parkinson’s is much more common in men.  In recent years, LJI scientists have found increasing evidence that … Read more