Ollie Super has moved in and out of cancer treatment since she was diagnosed with neuroblastoma as a toddler in foster care. Now 8, the second grader is dealing with it again. Her cancer came back late last year. Ollie’s parents, who adopted her in 2020, tried to sign her up for a clinical trial … Read more
Over the past few years interest has ramped up across industry and academia in bringing advanced cell therapy modalities such as chimeric antigen receptor T-cell (CAR-T) therapy to the field of autoimmune disease, with many directing their initial efforts at systemic lupus erythematosus (SLE) and lupus nephritis (LN). Thus far, late 2024 and early 2025 … Read more
Roswell Park Comprehensive Cancer Center is at the forefront of a new approach to cancer treatment, called CAR T-cell therapy. The little known, but highly promising technology breakthrough makes it possible for your body to fight cancer, often without invasive surgery, offering patients new hope for the possibility of long-term remission. However, a new survey … Read more
According to the Michael J. Fox Foundation, almost 1 million people in United States live with Parkinson disease (PD) and more than 6 million people in the world live with PD. Notably, the symptoms of PD and their severity vary widely, and can be different for every person. Although some treatment options for the disease … Read more
This article originally appeared on our sister site, Ophthalmology Times Europe®. Nanoscope Therapeutics’ MCO-010 (sonpiretigene isteparvovec), an investigational ambient-light activatable multi-characteristic opsin (MCO) gene therapy, showed the ability to restore vision in patients with retinitis pigmentosa (RP) in clinical data published Molecular Therapy.1 In the paper, which is entitled “A synthetic opsin restores vision in patients … Read more
Imagine a super-charged immune cell that can launch a focused attack on stubborn solid tumors – a smart fighter that destroys cancer cells for days without tiring. USC biomedical engineers have made this concept a reality, crafting what they have named the “EchoBack CAR T-cell,” which could soon be a game changer in the field … Read more
According to the Colorectal Cancer Alliance, colorectal cancer is the second deadliest cancer in the United States. In 2025 alone, 52,900 people in the US are expected to die from colorectal cancer. Although screening efforts and lifestyle changes have helped to reduce death rates during the past few decades, substantial unmet need remains, especially for … Read more
For all of 2024, our team was following the clinical development of targeted and novel engineered approaches to the treatment of patients with various medical disorders. These efforts included holding in-depth conversations with experts in the clinical care of these individuals, as well as in cell and gene therapy development, culminating in our coverage of … Read more