Lipid nanoparticles help CAR T cells melt pancreatic cancer barriers

Often diagnosed when surgery is no longer an option, pancreatic cancer is one of the most difficult cancers to treat and has one of the lowest rates of survival among major malignancies. Like many solid tumors, the most common type of pancreatic cancer, pancreatic ductal adenocarcinoma (PDAC), is shielded by the desmoplastic matrix-a dense barrier … Read more

New method creates longer lasting CAR T cells for cancer therapy

A research team led by Albert Einstein College of Medicine scientists has developed a new strategy to engineer immune cells that dramatically prolongs their effectiveness after being infused into patients to fight cancer and HIV, addressing a major limitation of current treatments. Their findings, published today in Science Advances, describe a manufacturing approach that, compared … Read more

Biomimetic platform enhances CAR T therapy for relapsed and refractory leukemia

Chimeric antigen receptor T (CAR T) cell therapy represents a milestone in leukemia treatment. CAR T works by genetically engineering a chimeric antigen receptor on the surface of the patient’s T cells to target specific antigens on leukemia cells, with the goal of identifying and eliminating them. However, clinical data show that more than 50% … Read more

Acute Myeloid Leukemia Fought With New AI Tool

Acute myeloid leukemia, or AML, is a rare and aggressive cancer that can affect people of all ages. Kiran Vanaja, an assistant research professor in bioengineering at Northeastern University, says that AML also has a high recurrence rate and no one-size-fits-all treatment option. Because AML impacts both blood and bone marrow, oncologists need samples of … Read more

Engineered Listeria boosts innate immunity against cancer

After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system to cause listeriosis, Daniel Portnoy and his colleagues have discovered a way to turn the bacteria into a potent booster of the immune system – and a potential weapon against cancer. Three years ago, Portnoy cofounded a … Read more

John Mauceri: Conductor Returns to Stage After Health Recovery

“`html BREAKING: John Mauceri‘s Cardiac Surgery Success BREAKING: John Mauceri’s Cardiac Surgery Success Award-winning conductor John Mauceri is back on stage after undergoing cardiac surgery to treat a… The post John Mauceri: Conductor Returns to Stage After Health Recovery appeared first on NewsyList. Source link

Maestro John Mauceri returns to the stage in renewed health

John Mauceri, an award-winning music conductor, author, and recording artist, is celebrating his return to the stage in better health following specialized cardiac surgery at NYU Langone Health to treat a rare and life-threatening heart condition. Maestro Mauceri’s illustrious career has taken him to the world’s most prestigious opera houses, symphony halls, Broadway stages and … Read more

Using gas stoves at home significantly increases cancer risk

New modeling reveals that high-emitting gas stoves can silently spread benzene throughout the entire home, raising cancer risk well beyond the kitchen, especially in small or unventilated dwellings. Study: Exposure and health risks of benzene from combustion by gas stoves: A modelling approach in U.S. homes. Image Credit: goodbishop / Shutterstock Gas stoves in the US burn … Read more

Refining the diagnosis of large granular lymphocytic leukemias and their mimics

Apr 10 2025 Large granular lymphocytic leukemias (LGLLs) are a heterogeneous group of rare chronic lymphoproliferative disorders characterized by the clonal proliferation of cytotoxic lymphocytes. Among them, T-cell LGLL (T-LGLL) and NK-cell LGLL (NK-LGLL) are the most prominent. Due to overlapping morphological, clinical, and immunophenotypic characteristics, distinguishing these disorders from related entities such as T-prolymphocytic … Read more