Dex Linked to Lower Delirium Incidence After Cardiac Surgery

TOPLINE: Administration of dexmedetomidine in patients undergoing cardiac surgery reduced the incidence of postoperative delirium by 38% but was associated with an increased risk for hypotension. METHODOLOGY: Researchers conducted a systematic review and meta-analysis of 18 randomized controlled trials involving 3904 patients undergoing any type of cardiac surgery. They compared the use of dexmedetomidine with … Read more

How GPs Can Safely Guide Patients Back to Sports

During a recent webinar hosted by the Scientific Society of General Medicine, Christophe Scavée, MD, head of the Department of Cardiology and Rhythmology Unit at Cliniques Universitaires Saint-Luc, Brussels, Belgium, discussed the critical role that general practitioners (GPs) play in sports screening. He outlined the essential steps GPs should take when patients want to start … Read more

CABG Still Superior to Stents Despite FAME 3 Endpoint Swap

What happened with the 5-year FAME 3 results is not right.  The reporting of this trial comparing stenting vs coronary artery bypass graft surgery (CABG) in patients with multivessel coronary artery disease (CAD) defies proper scientific principles. The FAME 3 Trial of Stents vs Surgery FAME 3 tested the best strategy to revascularize patients with … Read more

Noninvasive Stents as Good as Surgery for Triple-Vessel Disease

CHICAGO — Patients with severe triple-vessel heart disease who underwent a less-invasive stent procedure fared just as well as those who underwent open-heart bypass surgery after 5 years, the FAME 3 trial shows. The results are in marked contrast to earlier studies, which showed that patients with triple-vessel disease were less likely to die or … Read more

First Hours Crucial in New Guidance for Cardiogenic Shock

New clinical guidance to help cardiologists navigate the complexity of cardiogenic shock and assess possible cases within the first hour after onset introduces a memory aid — SUSPECT — which stands for symptoms/signs, urine output, sustained hypotension, perfusion, electrocardiogram/echocardiogram, congestion, and triage. The guidance is the first in a planned series from the American College … Read more

Better 5-Year Valve Performance With TAVI Than Surgery

TOPLINE: In patients with symptomatic severe aortic stenosis at intermediate or higher surgical risk, CoreValve or Evolut transcatheter aortic valve implantation (TAVI) was associated with a lower 5-year incidence of bioprosthetic valve dysfunction than surgery. Valve dysfunction was also associated with an increased risk for death and hospitalization, regardless of replacement therapy. METHODOLOGY: Researchers conducted … Read more

Transseptal Approach Shields Brain During Ablation

TOPLINE: The occurrence of acute brain lesions was lower with a transseptal puncture than with a conventional retrograde aortic approach in patients undergoing left ventricular catheter ablation, with no significant difference in the safety or efficacy profile between both approaches. METHODOLOGY: Previous studies suggested that catheter ablation for atrial fibrillation results in new brain lesions … Read more

Unlocking Heart Health: New GLP-1 Research Reveals Cardiovascular Advantages

Tirzepatide Shows Promise in Reducing cardiovascular Risk for Obese heart Failure Patients A new analysis of the SUMMIT trial reveals that the glucagon-like peptide 1 (GLP-1) agonist tirzepatide significantly lowers the risk of cardiovascular (CV) events in patients with obesity and heart failure with preserved ejection fraction (HFpEF). This benefit remains consistent nonetheless of whether … Read more

New GLP-1 Data Reinforce CV Benefit

The glucagon-like peptide 1 (GLP-1) agonist tirzepatide lowers the risk for cardiovascular (CV) events in patients with obesity and heart failure with preserved ejection fraction (HFpEF), whether they have general adiposity, measured with the body mass index (BMI), or central adiposity, measured with the waist-to-height ratio, showed a new analysis from the SUMMIT trial. This … Read more

Rethinking the Timing of Tricuspid Valve Repairs

With the introduction of percutaneous options, the role of surgery in the repair of dysfunctional tricuspid valves is being reevaluated in an effort to reduce the risk for end-stage disease. In the midst of transformative transcatheter approaches to repair diseased aortic and mitral valves, the tricuspid valve has been overshadowed, according to Michael E. Bowdish, … Read more